Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
about
RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovaryHuman RSPO1/R-spondin1 is expressed during early ovary development and augments β-catenin signalingFailure of SOX9 regulation in 46XY disorders of sex development with SRY, SOX9 and SF1 mutationsSOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epitheliumIdentification of SOX3 as an XX male sex reversal gene in mice and humansMale sex determination: insights into molecular mechanismsVascular endothelial growth factor A: just one of multiple mechanisms for sex-specific vascular development within the testis?SGF29 and Sry pathway in hepatocarcinogenesisHow to make a gonad: cellular mechanisms governing formation of the testes and ovariesMolecular players involved in temperature-dependent sex determination and sex differentiation in Teleost fishJust how conserved is vertebrate sex determination?Mammalian sex determination—insights from humans and mice.Plasticity of gene-regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpatorsThe PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiationTestis development requires the repression of Wnt4 by Fgf signalingGenetic control of testis developmentAnalyzing the coordinated gene network underlying temperature-dependent sex determination in reptilesEpigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machineryEliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine developmentBasic helix-loop-helix transcription factor TCF21 is a downstream target of the male sex determining gene SRYInsulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in miceAntagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in miceMicrosatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological noveltyA recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex developmentNR5A1 is a novel disease gene for 46,XX testicular and ovotesticular disorders of sex developmentIdentical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular TissuesSteroidogenic factor 1 differentially regulates fetal and adult leydig cell development in male miceTranscriptome Analysis for Identification of Genes Related to Gonad Differentiation, Growth, Immune Response and Marker Discovery in The Turbot (Scophthalmus maximus)Role of developmental factors in hypothalamic functionSteroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineageEpithelial-mesenchymal crosstalk in Wolffian duct and fetal testis cord development.Common functional genetic variants in catecholamine storage vesicle protein promoter motifs interact to trigger systemic hypertension.The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in miceA novel SRY missense mutation affecting nuclear import in a 46,XY female patient with bilateral gonadoblastoma.Complementary pathways in mammalian female sex determination.Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Sex determination in honeybees: two separate mechanisms induce and maintain the female pathway.Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elementsIdentification of SOX9 interaction sites in the genome of chondrocytesTransgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice.
P2860
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P2860
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@ast
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@en
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@nl
type
label
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@ast
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@en
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@nl
prefLabel
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@ast
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@en
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@nl
P356
P1433
P1476
Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer.
@en
P2093
Robin Lovell-Badge
Ryohei Sekido
P2888
P304
P356
10.1038/NATURE06944
P407
P577
2008-05-04T00:00:00Z
P6179
1004357452