Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies.
about
A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formationMonocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia.Atomic description of the immune complex involved in heparin-induced thrombocytopeniaEndothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopeniaRole of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications.Platelet and monocyte antigenic complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model.Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT.Disruption of PF4/H multimolecular complex formation with a minimally anticoagulant heparin (ODSH)PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI.Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia.Dynamic antibody-binding properties in the pathogenesis of HIT.Novel diagnostic assays for heparin-induced thrombocytopeniaDistinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4.Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis.Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophagesPlatelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia.Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT).The antigenic complex in HIT binds to B-cells via complement and complement receptor 2 (CD21).Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity.Platelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral AttachmentHuman tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system.Platelet factor 4 limits Th17 differentiation and cardiac allograft rejection.Assessing single-stranded oligonucleotide drug-induced effects in vitro reveals key risk factors for thrombocytopenia.The Role of Single-Molecule Force Spectroscopy in Unraveling Typical and Autoimmune Heparin-induced Thrombocytopenia.Neutrophil accumulation and NET release contribute to thrombosis in HIT
P2860
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P2860
Characterization of a murine monoclonal antibody that mimics heparin-induced thrombocytopenia antibodies.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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name
Characterization of a murine m ...... d thrombocytopenia antibodies.
@ast
Characterization of a murine m ...... d thrombocytopenia antibodies.
@en
Characterization of a murine m ...... d thrombocytopenia antibodies.
@nl
type
label
Characterization of a murine m ...... d thrombocytopenia antibodies.
@ast
Characterization of a murine m ...... d thrombocytopenia antibodies.
@en
Characterization of a murine m ...... d thrombocytopenia antibodies.
@nl
prefLabel
Characterization of a murine m ...... d thrombocytopenia antibodies.
@ast
Characterization of a murine m ...... d thrombocytopenia antibodies.
@en
Characterization of a murine m ...... d thrombocytopenia antibodies.
@nl
P2093
P1433
P1476
Characterization of a murine m ...... d thrombocytopenia antibodies.
@en
P2093
Arepally GM
P304
P407
P577
2000-03-01T00:00:00Z