Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA. - Wikidata - awgldk - TriplyDB

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

http://www.wikidata.org/entity/Q33339188

about

Alternative C-Terminal Helix Orientation Alters Chemokine Function: STRUCTURE OF THE ANTI-ANGIOGENIC CHEMOKINE, CXCL4L1 Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia.Atomic description of the immune complex involved in heparin-induced thrombocytopenia Endothelial antigen assembly leads to thrombotic complications in heparin-induced thrombocytopenia Heparin-induced thrombocytopenia: pathogenesis and management.PF4/heparin complexes are T cell-dependent antigens.Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications.Determinants of PF4/heparin immunogenicity Optimization of a murine immunization model for study of PF4/heparin antibodies.Pathobiology of secondary immune thrombocytopenia.Platelet and monocyte antigenic complexes in the pathogenesis of heparin-induced thrombocytopenia (HIT).Low-density lipoprotein apheresis reduces platelet factor 4 on the surface of platelets: a possible protective mechanism against heparin-induced thrombocytopenia and thrombosis.PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model.Review of continuing education course on hemostasis.Heparin-induced thrombocytopenia: present and future.CalDAG-GEFI deficiency protects mice in a novel model of Fcγ RIIA-mediated thrombosis and thrombocytopenia.The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies.PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI.Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia.Dynamic antibody-binding properties in the pathogenesis of HIT.Heparin-induced thrombocytopenia: the role of platelets genetic polymorphisms.Novel diagnostic assays for heparin-induced thrombocytopenia Critical role for mouse marginal zone B cells in PF4/heparin antibody production.Refractoriness to platelet transfusion in acute myeloid leukemia correlated with the optical density of anti-platelet factor 4/heparin antibodies.Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4.Distinguishing between anti-platelet factor 4/heparin antibodies that can and cannot cause heparin-induced thrombocytopenia.CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice.Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia.Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT).Single-molecule force spectroscopy applied to heparin-induced thrombocytopenia.Activated platelet-derived and leukocyte-derived circulating microparticles and the risk of thrombosis in heparin-induced thrombocytopenia: A role for pf4-bearing microparticles?Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity.Effect of pH and ionic strength on the binding strength of anti-PF4/polyanion antibodies.Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies The role of FcgammaRIIa as an inflammatory mediator in rheumatoid arthritis and systemic lupus erythematosus.Functional expression of IgA receptor FcalphaRI on human platelets.Mouse and human FcR effector functions.New Concepts and Mechanisms of Platelet Activation Signaling.ITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.

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Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

http://www.wikidata.org/entity/Q33339188

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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type

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Heparin-induced thrombocytopen ...... ctivation through FcgammaRIIA.

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Arepally GM

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