HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.
about
A naturally occurring LeuVal mutation in beta3-integrin impairs the HPA-1a epitope: the third allele of HPA-1.Management and outcome of 200 cases of fetomaternal alloimmune thrombocytopenia.Three novel beta3 domain-deletion peptides for the sensitive and specific detection of HPA-4 and six low frequency beta3-HPA antibodies.Immunologic and structural analysis of eight novel domain-deletion beta3 integrin peptides designed for detection of HPA-1 antibodies.A modified rapid monoclonal antibody-specific immobilization of platelet antigen assay for the detection of human platelet antigen (HPA) antibodies: a multicentre evaluation.Molecular insight into human platelet antigens: structural and evolutionary conservation analyses offer new perspective to immunogenic disordersDetection of human platelet antigen-1a alloantibodies in cases of fetomaternal alloimmune thrombocytopenia using recombinant β3 integrin fragments coupled to fluorescently labeled beads.Determination of human platelet antigen typing by molecular methods: Importance in diagnosis and early treatment of neonatal alloimmune thrombocytopenia.Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeuticsMapping the epitopes of antibodies.Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in Glanzmann Thrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort.
P2860
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P2860
HPA-1a phenotype-genotype discrepancy reveals a naturally occurring Arg93Gln substitution in the platelet beta 3 integrin that disrupts the HPA-1a epitope.
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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name
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@ast
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@en
type
label
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@ast
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@en
prefLabel
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@ast
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@en
P2093
P356
P1433
P1476
HPA-1a phenotype-genotype disc ...... t disrupts the HPA-1a epitope.
@en
P2093
David L Allen
Elisabeth Schaffner-Reckinger
Graham A Smith
Graham J Howkins
Michael F Murphy
Nelly Kieffer
Nicholas A Watkins
Nicolaas H C Brons
Paul Metcalfe
P304
P356
10.1182/BLOOD.V99.5.1833
P407
P577
2002-03-01T00:00:00Z