Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins
about
Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O bindingObstructing toxin pathways by targeted pore blockageA new model for pore formation by cholesterol-dependent cytolysinsCellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracisStructure of human C8 protein provides mechanistic insight into membrane pore formation by complement.Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen SpecificityStructural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59Structural Insights into Clostridium perfringens Delta Toxin Pore FormationCyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNApH dependence of listeriolysin O aggregation and pore-forming abilityCrucial role of perfringolysin O D1 domain in orchestrating structural transitions leading to membrane-perforating pores: a hydrogen-deuterium exchange study.Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysinsMonomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.Membrane assembly of the cholesterol-dependent cytolysin pore complex.Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membraneComprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysisTowards an understanding of the role of Clostridium perfringens toxins in human and animal disease.Development of a single-gene, signature-tag-based approach in combination with alanine mutagenesis to identify listeriolysin O residues critical for the in vivo survival of Listeria monocytogenes.Structure of human complement C8, a precursor to membrane attack.Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.Perfringolysin O: The Underrated Clostridium perfringens Toxin?Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation.Crystal structure of cytotoxin protein suilysin from Streptococcus suis.Granzymes drive a rapid listeriolysin O-induced T cell apoptosisReduction of streptolysin O (SLO) pore-forming activity enhances inflammasome activation.Clostridial toxins.Engineering a pH responsive pore forming protein.Toxins from bacteria.Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells.Biological activities of suilysin: role in Streptococcus suis pathogenesis.Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding.Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59.Structure-guided antigen engineering yields pneumolysin mutants suitable for vaccination against pneumococcal disease.
P2860
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P2860
Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@ast
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@en
type
label
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@ast
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@en
prefLabel
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@ast
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@en
P2093
P2860
P50
P1476
Structures of perfringolysin O ...... olesterol-dependent cytolysins
@en
P2093
Galina Polekhina
Rodney K Tweten
Susanne C Feil
P2860
P304
P356
10.1016/J.JMB.2007.01.042
P577
2007-01-23T00:00:00Z