Eflornithine for the treatment of human African trypanosomiasis.
about
Management of trypanosomiasis and leishmaniasisKinases as druggable targets in trypanosomatid protozoan parasitesDrug repurposing and human parasitic protozoan diseasesCrystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma bruceiTrial Watch: Proteasomal inhibitors for anticancer therapyNifurtimox plus Eflornithine for late-stage sleeping sickness in Uganda: a case seriesEliminating human African trypanosomiasis: where do we stand and what comes next?Immunobiology of African trypanosomes: need of alternative interventionsImportance of nonenteric protozoan infections in immunocompromised people.Oral putrescine restores virulence of ornithine decarboxylase-deficient Leishmania donovani in miceGenerating knock-in parasites: integration of an ornithine decarboxylase transgene into its chromosomal locus in Leishmania donovaniNutrient transport and pathogenesis in selected parasitic protozoa.Enantiospecific reassessment of the pharmacokinetics and pharmacodynamics of oral eflornithine against late-stage Trypanosoma brucei gambiense sleeping sickness.A method to improve the efficacy of topical eflornithine hydrochloride cream.A high-affinity putrescine-cadaverine transporter from Trypanosoma cruziSpermidine synthase is required for virulence of Leishmania donovani.Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.Human African trypanosomiasis of the CNS: current issues and challengesThe Trypanosoma cruzi Diamine Transporter Is Essential for Robust Infection of Mammalian Cells.Treatment options for second-stage gambiense human African trypanosomiasis.Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host.First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.The Trypanosoma brucei gambiense secretome impairs lipopolysaccharide-induced maturation, cytokine production, and allostimulatory capacity of dendritic cellsNovel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis.Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.Enantioselective and nonlinear intestinal absorption of eflornithine in the rat.The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain.Antiproliferative effect of dihydroxyacetone on Trypanosoma brucei bloodstream forms: cell cycle progression, subcellular alterations, and cell death.Vitamin B6-dependent enzymes in the human malaria parasite Plasmodium falciparum: a druggable target?Trypanosome prereplication machinery: a potential new target for an old problem.African sleeping sickness.Pentamidine movement across the murine blood-brain and blood-cerebrospinal fluid barriers: effect of trypanosome infection, combination therapy, P-glycoprotein, and multidrug resistance-associated protein.Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.Fexinidazole: A New Drug for African Sleeping Sickness on the Horizon.New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants.Salivarian Trypanosomosis: A Review of Parasites Involved, Their Global Distribution and Their Interaction With the Innate and Adaptive Mammalian Host Immune System
P2860
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P2860
Eflornithine for the treatment of human African trypanosomiasis.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Eflornithine for the treatment of human African trypanosomiasis.
@ast
Eflornithine for the treatment of human African trypanosomiasis.
@en
type
label
Eflornithine for the treatment of human African trypanosomiasis.
@ast
Eflornithine for the treatment of human African trypanosomiasis.
@en
prefLabel
Eflornithine for the treatment of human African trypanosomiasis.
@ast
Eflornithine for the treatment of human African trypanosomiasis.
@en
P921
P1476
Eflornithine for the treatment of human African trypanosomiasis.
@en
P2093
Christian Burri
P2888
P304
P356
10.1007/S00436-002-0766-5
P478
P577
2002-12-10T00:00:00Z
P6179
1075301943