Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus.
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Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen AllelesLymphocyte proliferation responses induced to broadly reactive Th peptides did not protect against equine infectious anemia virus challengeSelection of a rare neutralization-resistant variant following passive transfer of convalescent immune plasma in equine infectious anemia virus-challenged SCID horsesFailure of low-dose recombinant human IL-2 to support the survival of virus-specific CTL clones infused into severe combined immunodeficient foals: lack of correlation between in vitro activity and in vivo efficacy.Protective effects of broadly neutralizing immunoglobulin against homologous and heterologous equine infectious anemia virus infection in horses with severe combined immunodeficiency.Rev variation during persistent lentivirus infectionNaturally arising point mutations in non-essential domains of equine infectious anemia virus Rev alter Rev-dependent nuclear-export activity.Expression, refolding and preliminary X-ray crystallographic analysis of equine MHC class I molecule complexed with an EIAV-Env CTL epitopeCTL from EIAV carrier horses with diverse MHC class I alleles recognize epitope clusters in Gag matrix and capsid proteinsEarly detection of dominant Env-specific and subdominant Gag-specific CD8+ lymphocytes in equine infectious anemia virus-infected horses using major histocompatibility complex class I/peptide tetrameric complexes.A single amino acid difference within the alpha-2 domain of two naturally occurring equine MHC class I molecules alters the recognition of Gag and Rev epitopes by equine infectious anemia virus-specific CTL.Evaluation of high functional avidity CTL to Gag epitope clusters in EIAV carrier horsesCloning and large-scale expansion of epitope-specific equine cytotoxic T lymphocytes using an anti-equine CD3 monoclonal antibody and human recombinant IL-2Cytotoxic T lymphocytes in protection against equine infectious anemia virus.Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection.Viral load and clinical disease enhancement associated with a lentivirus cytotoxic T lymphocyte vaccine regimen.Horses naturally infected with EIAV harbor 2 distinct SU populations but are monophyletic with respect to IN.Deep sequencing and variant analysis of an Italian pathogenic field strain of equine infectious anaemia virus.Epitope shifting of gp90-specific cellular immune responses in EIAV-infected ponies.Experimental Rhodococcus equi and equine infectious anemia virus DNA vaccination in adult and neonatal horses: effect of IL-12, dose, and route.Envelope determinants of equine infectious anemia virus vaccine protection and the effects of sequence variation on immune recognition.Molecular detection, epidemiology, and genetic characterization of novel European field isolates of equine infectious anemia virus.The determination of in vivo envelope-specific cell-mediated immune responses in equine infectious anemia virus-infected ponies.
P2860
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P2860
Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus.
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Epitope specificity is critica ...... quine infectious anemia virus.
@ast
Epitope specificity is critica ...... quine infectious anemia virus.
@en
type
label
Epitope specificity is critica ...... quine infectious anemia virus.
@ast
Epitope specificity is critica ...... quine infectious anemia virus.
@en
prefLabel
Epitope specificity is critica ...... quine infectious anemia virus.
@ast
Epitope specificity is critica ...... quine infectious anemia virus.
@en
P2093
P2860
P1433
P1476
Epitope specificity is critica ...... quine infectious anemia virus.
@en
P2093
Baoshan Zhang
Matt H Littke
Steven R Leib
Travis C McGuire
P2860
P304
P356
10.1016/S0042-6822(03)00344-1
P407
P577
2003-09-01T00:00:00Z