Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. - Wikidata - awgldk - TriplyDB

Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries.

Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries.

http://www.wikidata.org/entity/Q33355751

about

Privileged scaffolds for library design and drug discovery Diversity-Oriented Synthesis of Natural-Product-like Libraries Containing a 3-Methylbenzofuran Moiety for the Discovery of New Chemical Elicitors Synthesis of unprecedented scaffold diversity.Naturally diverse: highlights in versatile synthetic methods enabling target- and diversity-oriented synthesis.Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.Branching cascades: a concise synthetic strategy targeting diverse and complex molecular frameworks.Towards the systematic exploration of chemical space.Skeletal diversity via cationic rearrangements of substituted dihydropyrans.A series of structurally novel heterotricyclic alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor-selective antagonists.Evolution of a strategy for preparing bioactive small molecules by sequential multicomponent assembly processes, cyclizations, and diversification A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.Molecular library synthesis using complex substrates: expanding the framework of triterpenoids.The spinosyn family of insecticides: realizing the potential of natural products research.Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.De novo branching cascades for structural and functional diversity in small molecules.Generation of N-Heterocycles via Tandem Reactions of N '-(2-Alkynylbenzylidene)hydrazides.Identification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library.Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.Design and synthesis of novel PEG-conjugated 20(S)-camptothecin sulfonylamidine derivatives with potent in vitro antitumor activity via Cu-catalyzed three-component reaction Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages.4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle.Recent derivatives from smaller classes of fermentation-derived antibacterials.2-Alkynylbenzaldoxime: a versatile building block for the generation of N-heterocycles.Design and synthesis of analogues of natural products.A concise total synthesis of deoxyschizandrin and exploration of its antiproliferative effects and those of structurally related derivatives.Targeting historically refractory interfaces: a partnership model that accelerates drug discovery within an expanded haystack.Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck-Suzuki reaction.Diversity-oriented synthesis of 13- to 18-membered macrolactams via ring-closing metathesis.Synthesis of natural-product-like molecules with over eighty distinct scaffolds Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks.Diversity-oriented synthesis of analogues of the novel macrocyclic peptide FR-225497 through late stage functionalization.Generation of 4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxides via a reaction of trifluoromethanesulfanylamide with 2-(2-alkynyl)benzenesulfonamide.An Enyne Cope Rearrangement Enables Polycycloalkane Synthesis from Readily Available Starting Materials.Natural Products as Platforms To Overcome Antibiotic Resistance.Yin and Yang in medicinal chemistry: what does drug-likeness mean?Expeditious divergent synthetic approach to polycyclic terpene-like molecules.Base-controlled [3+3] cycloaddition of isoquinoline N-oxides with azaoxyallyl cations.Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.Synthesis of multi ring-fused imidazo [1,2-a]isoquinoline-based fluorescent scaffold as anti-Herpetic agent.

P2860

Q24604575-7DBFC2FA-969F-4395-864D-EA022DEE03E9 Q28817632-254932F1-C768-4EB0-8BB6-E4DC60DB0927 Q33399155-739D561B-BF78-48A6-8DF7-F754DD510A1D Q33431379-081982A7-B85C-4FA3-8822-5E87B626E7E5 Q33849709-5F4C2BE1-91D7-4C3E-964E-46BCC056AF99 Q33852396-D4F4FFE2-2A2E-490A-BF55-A56A5AA3D722 Q33934236-B8C42752-C0E3-450F-BC74-3CC4CADF65A2 Q34039203-5AB8CCD5-6A74-4AF1-BD69-EE63973536CC Q34118726-571AA3D3-7579-43DE-A461-CF154E94A95D Q34124829-82688186-1908-41C2-8E66-0EED50524828 Q34207033-6C465555-BF87-429D-A6CF-90AF195B989E Q34378812-1459F77F-D651-4548-BBBE-5A24D053B93A Q34514231-0A796038-649A-4E18-8AC3-C972108455B4 Q34616659-D546A2FC-9331-4C67-AB6A-4EBD886539BF Q35052785-D1F9815D-8211-47E9-A24F-463B825BFE80 Q35580160-F58BF198-4641-4A4E-9E96-B1E873A7A9C3 Q35817650-D899187B-3A01-4607-8767-40F5F663C9AE Q36172912-15FD9E30-1FF9-4A2C-A758-1A9FDA7410C6 Q36229686-3C8EADCC-ECBC-472B-9902-2921275AE03F Q36623111-3DD4C7A8-51CE-4502-98FC-6358D9B29425 Q36724073-8F3C9B3B-AE9D-48E6-BEE2-3527F5DE9276 Q37700104-B8136F30-5B21-4D63-B3BD-42472378A26C Q37964009-206FA6EB-7CA5-4635-8A3F-752966787FCC Q38258256-2B486A8A-11D5-4936-91DD-145F8E543649 Q38398596-3BC8AD2C-41FC-497C-B90D-A37CCAB31D08 Q39401134-D9E7F183-F593-4B24-8365-E7EC1A87AF82 Q39967137-E22E0950-BC12-46CC-A888-63DAA221A6B4 Q41954312-93DDDDDC-5729-41A8-A686-F874E774828B Q42106213-BC324711-BCE7-4D83-A2CE-B5405399A094 Q42114290-D56076AB-F3C7-4576-BEF9-DF11DE05DAE1 Q42117508-EE973E33-83A2-45AD-9F0A-1011ECF9C71B Q42137756-807DD357-102F-4AC3-AF39-F0B1EFAE0052 Q45902607-D323F9FF-C0E4-4CA6-B1DC-65D092997BCB Q48136720-930666F9-26E2-48A7-A989-C3D5731D01CA Q48281604-26977B30-3C8D-4153-93A6-339710F3CA1B Q51712154-6983CAC0-89B1-4FAA-9693-88F1723F495E Q53780722-3B4C20EA-8653-4319-9AC0-84A734E419AC Q54019391-83A9E88C-F4D0-4565-BE41-0CE5F2C10315 Q54369237-D3250162-8897-421F-AA39-2AFE27AEEA92 Q55085136-2EE45C8A-AE38-4F97-8982-210FDC38FDA6

P2860

Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries.

http://www.wikidata.org/entity/Q33355751

description

2008 nî lūn-bûn

@nan

2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Natural products as an inspira ...... bioactive compound libraries.

@ast

Natural products as an inspira ...... bioactive compound libraries.

@en

Natural products as an inspira ...... bioactive compound libraries.

@en-gb

type

label

Natural products as an inspira ...... bioactive compound libraries.

@ast

Natural products as an inspira ...... bioactive compound libraries.

@en

Natural products as an inspira ...... bioactive compound libraries.

@en-gb

prefLabel

Natural products as an inspira ...... bioactive compound libraries.

@ast

Natural products as an inspira ...... bioactive compound libraries.

@en

Natural products as an inspira ...... bioactive compound libraries.

@en-gb

P1433

Q33355751-88DF7E68-015D-44E0-809B-B5E8CAA13568

P1476

Q33355751-4CB326BC-2406-4435-A975-3A2631D0B9B6

P2093

Q33355751-08547445-4697-41C4-B8E0-F9E792FC293A

Q33355751-70A2F012-0C5B-4D33-A655-819D1DC95E56

Q33355751-B3B2C473-9623-4A28-B7BD-2E257E1500D6

P275

Q33355751-88BD59DF-BBBA-413E-9BCC-06B1B5AA7B9B

P2860

Q33355751-00B4B9B8-7725-41E7-A756-F26CA590E80C

Q33355751-06402F66-6F35-497D-A342-80F91DE339A1

Q33355751-07C1639F-34DD-41B0-86D8-846056DE77F4

Q33355751-0CE2F23B-9BFB-4C15-9480-5BD7D3014FF9

Q33355751-0E1ECD5F-66A8-4DE7-900A-895AA551ECCA

Q33355751-10334779-75A1-49FA-8D35-C9CA8CAE25DD

Q33355751-14798546-231A-405A-842F-66EDCBC73C1C

Q33355751-17E44B2C-C566-40DC-A468-B5BEE2E727A0

Q33355751-19080B11-C932-4D37-8971-83F59FD245E9

Q33355751-2210D453-BA2D-4590-A788-7BFC2A01C78D

P304

Q33355751-A273BD30-D934-4105-AF4B-5DF8B4C90030

P31

Q33355751-834F9407-90F5-4245-9584-5A08A9EDCDA8

Q33355751-93D97907-57EA-4991-8229-0A1F22FC1E4F

P356

Q33355751-88727AC8-85ED-43BE-9DBB-393091E5FCE6

P433

Q33355751-1ABF2C06-8678-44E0-B8B7-342378E76BE2

P478

Q33355751-FFD96A99-CA9A-40CD-BC1F-2BE907EF5D0E

P50

Q33355751-7879749F-C5D5-41DD-A1B7-988489C87ADE

Q33355751-AB0393F3-D231-46E2-AC55-FD90EA3B7D7E

P577

Q33355751-3DFA3AD2-91AA-4742-A6BD-38F8177DFD6B

Q33355751-E0C4E951-93ED-4C87-B7CD-04C6233E6DF6

P5875

Q33355751-EA3C28C5-FE4D-4910-A379-00C6A50C6343

P698

Q33355751-8626DFF3-03E1-42FA-892A-358074F958CB

P921

Q33355751-519402CE-DC84-4D7A-819F-930E91B59E67

P932

Q33355751-8EB5639E-B433-4356-9009-04CC555A8587

P356

P1433

Natural Product Reports

P1476

Natural products as an inspira ...... bioactive compound libraries.

@en

P2093

Catherine O'Leary-Steele

http://www.w3.org/2001/XMLSchema#string

Christopher Cordier

http://www.w3.org/2001/XMLSchema#string

Sarah Murrison

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution-NonCommercial

P2860

Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin

Genomewide studies of histone deacetylase function in yeast

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor

Chemical variation of natural-product-like scaffolds: design, synthesis, and biological activity of fused bicyclic acetal derivatives

A planning strategy for diversity-oriented synthesis

Short synthesis of skeletally and stereochemically diverse small molecules by coupling petasis condensation reactions to cyclization reactions

Small molecules: the missing link in the central dogma

P304

719-737

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1039/B706296F

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-04-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

2008-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23133986

http://www.w3.org/2001/XMLSchema#string

P698

18663392

http://www.w3.org/2001/XMLSchema#string

P921

biomedical investigative technique

P932

2496956

http://www.w3.org/2001/XMLSchema#string