The threat of instability: neurodegeneration predicted by protein destabilization and aggregation propensity
about
Perturbation of the Monomer–Monomer Interfaces of the Benzoylformate Decarboxylase TetramerEvolution in health and medicine Sackler colloquium: Somatic evolutionary genomics: mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration.The contrasting effect of macromolecular crowding on amyloid fibril formation.The structural biochemistry of the superoxide dismutases.Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies.Destabilization of the dimer interface is a common consequence of diverse ALS-associated mutations in metal free SOD1Size-selective concentration and label-free characterization of protein aggregates using a Raman active nanofluidic device.A theoretical study on Zn binding loop mutants instigating destabilization and metal binding loss in human SOD1 protein.
P2860
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P2860
The threat of instability: neurodegeneration predicted by protein destabilization and aggregation propensity
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The threat of instability: neu ...... ion and aggregation propensity
@ast
The threat of instability: neu ...... ion and aggregation propensity
@en
type
label
The threat of instability: neu ...... ion and aggregation propensity
@ast
The threat of instability: neu ...... ion and aggregation propensity
@en
prefLabel
The threat of instability: neu ...... ion and aggregation propensity
@ast
The threat of instability: neu ...... ion and aggregation propensity
@en
P2860
P1433
P1476
The threat of instability: neu ...... ion and aggregation propensity
@en
P2093
Elizabeth M Meiering
P2860
P356
10.1371/JOURNAL.PBIO.0060193
P407
P577
2008-07-01T00:00:00Z