Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
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The genomes of four tapeworm species reveal adaptations to parasitismThe new deal: a potential role for secreted vesicles in innate immunity and tumor progressionMebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in miceRepositioning approved drugs for the treatment of problematic cancers using a screening approach.Drug repositioning: a machine-learning approach through data integration.Repurposing Drugs in Oncology (ReDO)-mebendazole as an anti-cancer agentRepurposing the antihelmintic mebendazole as a hedgehog inhibitor.3-Bromopyruvate inhibits human gastric cancer tumor growth in nude mice via the inhibition of glycolysis.Antiparasitic mebendazole shows survival benefit in 2 preclinical models of glioblastoma multiforme.Anti-Neoplastic Cytotoxicity of Gemcitabine-(C4-amide)-[anti-EGFR] in Dual-combination with Epirubicin-(C3-amide)-[anti-HER2/neu] against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3) and the Complementary Effect of Mebendazole.Effective treatment of diverse medulloblastoma models with mebendazole and its impact on tumor angiogenesis.Influence of Alternative Tubulin Inhibitors on the Potency of a Epirubicin-Immunochemotherapeutic Synthesized with an Ultra Violet Light-Activated Intermediate: Influence of incorporating an internal/integral disulfide bond structure and AlternativeBrain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC).Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical modelExisting drugs and their application in drug discovery targeting cancer stem cells.Vinblastine and antihelmintic mebendazole potentiate temozolomide in resistant gliomas.Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro.Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines.Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen.The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanomaEffect of squalane on mebendazole-loaded Compritol® nanoparticles.Diallyl trisulfide induces apoptosis of human basal cell carcinoma cells via endoplasmic reticulum stress and the mitochondrial pathway.miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis.Albendazole sensitizes cancer cells to ionizing radiation.Inhibition of the CRAF/prohibitin interaction reverses CRAF-dependent resistance to vemurafenib.Gemcitabine-(C4-amide)-[anti-HER2/neu] Anti-Neoplastic Cytotoxicity in Dual Combination with Mebendazole against Chemotherapeutic-Resistant Mammary Adenocarcinoma.Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase InhibitorRepurposing drugs in oncology (ReDO)-cimetidine as an anti-cancer agentThe unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding.Design, synthesis and biological evaluation of chrysin benzimidazole derivatives as potential anticancer agents.In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells.Finding melanoma drugs through a probabilistic knowledge graph
P2860
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P2860
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@ast
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@en
type
label
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@ast
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@en
prefLabel
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@ast
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@en
P2093
P1476
Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells.
@en
P2093
Adrianna Rodriguez
Iman Osman
Nicole Doudican
P304
P356
10.1158/1541-7786.MCR-07-2159
P50
P577
2008-07-30T00:00:00Z