A phase I trial of aprinocarsen (ISIS 3521/LY900003), an antisense inhibitor of protein kinase C-alpha administered as a 24-hour weekly infusion schedule in patients with advanced cancer.
about
PKC alpha affects cell cycle progression and proliferation in human RPE cells through the downregulation of p27kip1Triggering of RNA interference with RNA-RNA, RNA-DNA, and DNA-RNA nanoparticles.Restoring dystrophin expression in duchenne muscular dystrophy muscle progress in exon skipping and stop codon read through.Protein kinase C, an elusive therapeutic target?Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.Nucleic acid drugs in the clinic.Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics.Protein kinase C and cardiac dysfunction: a review.
P2860
Q33518455-94DC32A0-34A2-496C-838A-58042687693DQ35027155-D474717D-AD74-49DD-B3B4-F37E888F219DQ35072755-D8D51762-645A-4A32-9E6D-50E1FCC3F592Q37141320-4E54F9B1-EBE6-4DCB-8D5A-CD50869E30FAQ37321859-276ECB85-E301-41B7-9D9D-E26EFACCC7C6Q38088755-31353AD0-54FE-4F91-AA37-4D99F3F8E4C4Q38504825-FDF3FBAE-35CF-43C6-8C35-03E852B3156FQ39432092-683B6E6A-279B-4F3A-8A3F-45F6DFE10E4F
P2860
A phase I trial of aprinocarsen (ISIS 3521/LY900003), an antisense inhibitor of protein kinase C-alpha administered as a 24-hour weekly infusion schedule in patients with advanced cancer.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A phase I trial of aprinocarse ...... patients with advanced cancer.
@ast
A phase I trial of aprinocarse ...... patients with advanced cancer.
@en
type
label
A phase I trial of aprinocarse ...... patients with advanced cancer.
@ast
A phase I trial of aprinocarse ...... patients with advanced cancer.
@en
prefLabel
A phase I trial of aprinocarse ...... patients with advanced cancer.
@ast
A phase I trial of aprinocarse ...... patients with advanced cancer.
@en
P2093
P1476
A phase I trial of aprinocarse ...... patients with advanced cancer.
@en
P2093
Bert L Lum
Branimir I Sikic
F Andrew Dorr
George A Fisher
Joanne Halsey
Jon T Holmlund
Ranjana Advani
Richard S Geary
T Jesse Kwoh
P2888
P304
P356
10.1007/S10637-005-2906-0
P577
2005-10-01T00:00:00Z
P5875
P6179
1022728991