Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF.
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Comments on the mechanisms of action of radiation protective agents: basis components and their polyvalence5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosisMedical countermeasures for unwanted CBRN exposures: part II radiological and nuclear threats with review of recent countermeasure patentsFilgrastim improves survival in lethally irradiated nonhuman primatesThe ability of filgrastim to mitigate mortality following LD50/60 total-body irradiation is administration time-dependent.Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models.Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiationLymphoid and Myeloid Recovery in Rhesus Macaques Following Total Body X-IrradiationAllogeneic non-adherent bone marrow cells facilitate hematopoietic recovery but do not lead to allogeneic engraftmentNotch-Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients.Endothelial cells mitigate DNA damage and promote the regeneration of hematopoietic stem cells after radiation injury.Evaluation of hydration and nutritional gels as supportive care after total-body irradiation in mice (Mus musculus).The prolonged gastrointestinal syndrome in rhesus macaques: the relationship between gastrointestinal, hematopoietic, and delayed multi-organ sequelae following acute, potentially lethal, partial-body irradiation.Animal models for medical countermeasures to radiation exposure.Late infusion of cloned marrow fibroblasts stimulates endogenous recovery from radiation-induced lung injury.Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile.Dose-modifying factor for captopril for mitigation of radiation injury to normal lungEstablishment of Early Endpoints in Mouse Total-Body Irradiation Model.Radiation injury after a nuclear detonation: medical consequences and the need for scarce resources allocation.The Gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiationEstablishing a murine model of the hematopoietic syndrome of the acute radiation syndromeDietary antioxidants protect hematopoietic cells and improve animal survival after total-body irradiationPEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome.Survival efficacy of the PEGylated G-CSFs Maxy-G34 and neulasta in a mouse model of lethal H-ARS, and residual bone marrow damage in treated survivors.A nonhuman primate model of the hematopoietic acute radiation syndrome plus medical management.History and development of radiation-protective agents.Pegylated G-CSF inhibits blood cell depletion, increases platelets, blocks splenomegaly, and improves survival after whole-body ionizing irradiation but not after irradiation combined with burnRadiobiological basis in management of accidental radiation exposure.ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs--threshold doses for tissue reactions in a radiation protection context.Animal models for acute radiation syndrome drug discovery.Screening of antimicrobial agents for in vitro radiation protection and mitigation capacity, including those used in supportive care regimens for bone marrow transplant recipients.Combined Therapy of Pegylated G-CSF and Alxn4100TPO Improves Survival and Mitigates Acute Radiation Syndrome after Whole-Body Ionizing Irradiation alone and Followed by Wound Trauma.Acute radiation enteritis caused by dose-dependent radiation exposure in dogs: experimental research.Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs.Renal dysfunction after total body irradiation: dose-effect relationship: in regard to Kal and van Kempen-Harteveld (Int J Radiat Oncol Biol Phys 2006;65:1228-1232).Non-human Primate Total-body Irradiation Model with Limited and Full Medical Supportive Care Including Filgrastim for Biodosimetry and Injury Assessment.Protein biomarkers for enhancement of radiation dose and injury assessment in nonhuman primate total-body irradiation model.
P2860
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P2860
Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF.
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Defining the full therapeutic ...... plus administration of G-CSF.
@ast
Defining the full therapeutic ...... plus administration of G-CSF.
@en
type
label
Defining the full therapeutic ...... plus administration of G-CSF.
@ast
Defining the full therapeutic ...... plus administration of G-CSF.
@en
prefLabel
Defining the full therapeutic ...... plus administration of G-CSF.
@ast
Defining the full therapeutic ...... plus administration of G-CSF.
@en
P2093
P1433
P1476
Defining the full therapeutic ...... plus administration of G-CSF.
@en
P2093
Ann M Farese
Thomas J MacVittie
William Jackson
P304
P356
10.1097/01.HP.0000173143.69659.5B
P577
2005-11-01T00:00:00Z