Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants - Wikidata - awgldk - TriplyDB

Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants

Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants

http://www.wikidata.org/entity/Q33369591

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Plasmid-mediated quinolone resistance: a multifaceted threat Update on infections caused by Stenotrophomonas maltophilia with particular attention to resistance mechanisms and therapeutic options Stenotrophomonas maltophilia: an emerging global opportunistic pathogen Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacterium The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia Transferable quinolone resistance in Vibrio cholerae.A mutational analysis and molecular dynamics simulation of quinolone resistance proteins QnrA1 and QnrC from Proteus mirabilis.Wastewater irrigation increases the abundance of potentially harmful gammaproteobacteria in soils in Mezquital Valley, Mexico.Differential epigenetic compatibility of qnr antibiotic resistance determinants with the chromosome of Escherichia coli.Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences.Plasmid-mediated quinolone resistance.Determination of pentapeptide repeat units in Qnr proteins by the structure-based alignment approach.Stenotrophomonas maltophilia strains replicate and persist in the murine lung, but to significantly different degrees Origin and evolution of antibiotic resistance: the common mechanisms of emergence and spread in water bodies.The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response RNASeq Based Transcriptional Profiling of Pseudomonas aeruginosa PA14 after Short- and Long-Term Anoxic Cultivation in Synthetic Cystic Fibrosis Sputum Medium.Comparative Genomics of Environmental and Clinical Stenotrophomonas maltophilia Strains with Different Antibiotic Resistance Profiles Mechanisms of drug resistance: quinolone resistance.Characterization of Vibrio fluvialis qnrVC5 Gene in Native and Heterologous Hosts: Synergy of qnrVC5 with other Determinants in Conferring Quinolone Resistance Phylogenetic analysis of chromosomally determined qnr and related proteins.qnrD, a novel gene conferring transferable quinolone resistance in Salmonella enterica serovar Kentucky and Bovismorbificans strains of human origin.New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis.A global view of antibiotic resistance.Stenotrophomonas maltophilia drug resistance.Stenotrophomonas maltophilia: emerging disease patterns and challenges for treatment.Metabolic regulation of antibiotic resistance.Distribution of Class I Integron and smqnr Resistance Gene Among Stenotrophomonas maltophilia Isolated from Clinical Samples in Iran.Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance.Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.Quinolone resistance: much more than predicted.Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets.Natural antibiotic resistance and contamination by antibiotic resistance determinants: the two ages in the evolution of resistance to antimicrobials.Prevalence of Smqnr and plasmid-mediated quinolone resistance determinants in clinical isolates of Stenotrophomonas maltophilia from Japan: novel variants of Smqnr.The Inactivation of intrinsic antibiotic resistance determinants widens the mutant selection window for quinolones in Stenotrophomonas maltophilia.Identification and characterization of a serious multidrug resistant Stenotrophomonas maltophilia strain in China.Smqnr variants in clinical isolates of Stenotrophomonas maltophilia in Brazil.Functional verification of computationally predicted qnr genes.Whole-genome sequence of Stenotrophomonas maltophilia D457, a clinical isolate and a model strain.SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia.

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Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants

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BMC Microbiology

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Predictive analysis of transmi ...... vel family of Qnr determinants

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Alvaro Hernández

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José M Rodríguez-Martínez

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Luis Martínez-Martínez

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María B Sánchez

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P2860

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia

The COG database: new developments in phylogenetic classification of proteins from complete genomes

Pentapeptide repeat proteins

Structure and distribution of pentapeptide repeats in bacteria

Environmental genome shotgun sequencing of the Sargasso Sea

A genomic perspective on protein families

The Jalview Java alignment editor

Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia.

Intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA

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