about
Animal models for thrombotic thrombocytopenic purpuraBF066, a novel dual target antiplatelet agent without significant bleedingPeroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis.Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage AtherosclerosisThe role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis.Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings.Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.Red blood cells mediate the onset of thrombosis in the ferric chloride murine model.Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor string formation under flow in a free-thiol-dependent manner.Platelet adhesion receptors do not modulate infarct volume after a photochemically induced stroke in mice.Bench-to-bedside review: thrombocytopenia-associated multiple organ failure--a newly appreciated syndrome in the critically illADAMTS13 and microvascular thrombosisThrombotic thrombocytopenic purpura: a thrombotic disorder caused by ADAMTS13 deficiencyThe combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis.The kidney in thrombotic thrombocytopenic purpura.Intensive plasma exchange increases a disintegrin and metalloprotease with thrombospondin motifs-13 activity and reverses organ dysfunction in children with thrombocytopenia-associated multiple organ failureCorrection of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes.The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation.Adenoviral-mediated gene transfer restores plasma ADAMTS13 antigen and activity in ADAMTS13 knockout mice.Targeting von Willebrand factor and platelet glycoprotein Ib receptor.A high LDH to AST ratio helps to differentiate pregnancy-associated thrombotic thrombocytopenic purpura (TTP) from HELLP syndrome.Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura.AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpuraPlatelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model.Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpuraDiagnosis and management of acquired thrombotic thrombocytopenic purpura in southeast China: a single center experience of 60 cases.Thrombosis: tangled up in NETs.Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13.Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease.In vivo imaging analysis of the interaction between unusually large von Willebrand factor multimers and platelets on the surface of vascular wall.ADAMTS13 controls vascular remodeling by modifying VWF reactivity during stroke recovery.von Willebrand factor: an emerging target in stroke therapy.Phenotypic expression of ADAMTS13 in glomerular endothelial cellsvon Willebrand factor, Jedi knight of the bloodstreamCurrent status in diagnosis and treatment of hereditary thrombotic thrombocytopenic purpura.Platelet adhesion under flow.Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in miceThe development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A.Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Systemic antithrombotic effects of ADAMTS13.
@ast
Systemic antithrombotic effects of ADAMTS13.
@en
type
label
Systemic antithrombotic effects of ADAMTS13.
@ast
Systemic antithrombotic effects of ADAMTS13.
@en
prefLabel
Systemic antithrombotic effects of ADAMTS13.
@ast
Systemic antithrombotic effects of ADAMTS13.
@en
P2093
P2860
P356
P1476
Systemic antithrombotic effects of ADAMTS13.
@en
P2093
Colin B Lamb
David G Motto
David Ginsburg
Denisa D Wagner
Friedrich Scheiflinger
Michael Dockal
Wolfgang Bergmeier
P2860
P304
P356
10.1084/JEM.20051732
P407
P577
2006-03-13T00:00:00Z