Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.
about
Mycobacterial outer membranes: in search of proteinsThe Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residueInhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membraneIdentification of a Desaturase Involved in Mycolic Acid Biosynthesis in Mycobacterium smegmatisIdentification of KasA as the cellular target of an anti-tubercular scaffoldThe Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis.New approaches to target the mycolic acid biosynthesis pathway for the development of tuberculosis therapeutics.MmpL11 protein transports mycolic acid-containing lipids to the mycobacterial cell wall and contributes to biofilm formation in Mycobacterium smegmatis.Mycolic acids: deciphering and targeting the Achilles' heel of the tubercle bacillusMycobacterial cell wall biosynthesis: a multifaceted antibiotic target.Analysis of Corynebacterium diphtheriae macrophage interaction: Dispensability of corynomycolic acids for inhibition of phagolysosome maturation and identification of a new gene involved in synthesis of the corynomycolic acid layer.
P2860
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P2860
Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing beta-oxo-mycolic acid analogs and accumulation of ketones.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@ast
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@en
type
label
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@ast
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@en
prefLabel
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@ast
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@en
P2093
P2860
P1476
Loss of a mycobacterial gene e ...... s and accumulation of ketones.
@en
P2093
Albel Singh
Alistair K Brown
Apoorva Bhatt
David E Minnikin
P2860
P304
P356
10.1016/J.CHEMBIOL.2008.07.007
P577
2008-09-01T00:00:00Z