Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing.
about
Integrated decision strategies for skin sensitization hazardIn vitro methods for hazard assessment of industrial chemicals - opportunities and challengesIntegrated Computational Solution for Predicting Skin Sensitization Potential of MoleculesMultivariate Models for Prediction of Human Skin Sensitization HazardPredicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships.In-silico experiments of zebrafish behaviour: modeling swimming in three dimensions.Acute toxicity testing of chemicals-Opportunities to avoid redundant testing and use alternative approaches.Non-animal sensitization testing: state-of-the-art.Perspectives on Non-Animal Alternatives for Assessing Sensitization Potential in Allergic Contact Dermatitis.Non-animal test methods for predicting skin sensitization potentials.Penetration and haptenation of p-phenylenediamine.Reporter cell lines for skin sensitization testing.Prediction of skin sensitization potency using machine learning approaches.Development of novel in vitro photosafety assays focused on the Keap1-Nrf2-ARE pathway.Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization.Evaluation of in silico tools to predict the skin sensitization potential of chemicals.Understanding bioavailability and toxicity of sediment-associated contaminants by combining passive sampling with in vitro bioassays in an urban river catchment.Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice.A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation.Evaluation of the skin sensitization potential of chemicals in THP-1/keratinocyte co-cultures.Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy.Water quality assessment using the AREc32 reporter gene assay indicative of the oxidative stress response pathway.Fragment-based prediction of skin sensitization using recursive partitioning.Development of an artificial neural network model for risk assessment of skin sensitization using human cell line activation test, direct peptide reactivity assay, KeratinoSens™ and in silico structure alert parameter.Development of a multiparametric in vitro model of skin sensitization.
P2860
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P2860
Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Filling the concept with data: ...... ee skin sensitization testing.
@ast
Filling the concept with data: ...... ee skin sensitization testing.
@en
type
label
Filling the concept with data: ...... ee skin sensitization testing.
@ast
Filling the concept with data: ...... ee skin sensitization testing.
@en
prefLabel
Filling the concept with data: ...... ee skin sensitization testing.
@ast
Filling the concept with data: ...... ee skin sensitization testing.
@en
P2860
P356
P1476
Filling the concept with data: ...... ee skin sensitization testing.
@en
P2093
Graham Ellis
Roger Emter
P2860
P304
P356
10.1093/TOXSCI/KFN204
P577
2008-10-01T00:00:00Z