HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease. - Wikidata - awgldk - TriplyDB

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

http://www.wikidata.org/entity/Q33375075

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Evasion of the Immune Response by Trypanosoma cruzi during Acute Infection CD8+ T cells in Trypanosoma cruzi infection Modulation of Trypanosoma cruzi-specific T-cell responses after chemotherapy for chronic Chagas disease Changes in Trypanosoma cruzi-specific immune responses after treatment: surrogate markers of treatment efficacy.CD8(+) T cell-mediated immunity during Trypanosoma cruzi infection: a path for vaccine development?Methodological advances in drug discovery for Chagas disease.Presence of antigen-experienced T cells with low grade of differentiation and proliferative potential in chronic Chagas disease myocarditis.Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease Chagasic patients are able to respond against a viral antigen from influenza virus.Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescence Low frequency of circulating CD8+ T stem cell memory cells in chronic chagasic patients with severe forms of the disease.Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity.Perturbed T cell IL-7 receptor signaling in chronic Chagas disease.Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.Improved proteomic approach for the discovery of potential vaccine targets in Trypanosoma cruzi.Biomarkers of therapeutic responses in chronic Chagas disease: state of the art and future perspectives.Protective human leucocyte antigen haplotype, HLA-DRB1*01-B*14, against chronic Chagas disease in Bolivia.An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8(+) T cell epitopes.Methodological approach to the ex vivo expansion and detection of T. cruzi-specific T cells from chronic Chagas disease patients.Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study.CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance.Chagas' disease: an update on immune mechanisms and therapeutic strategies CD8+ T cells in Trypanosoma cruzi infection.New, combined, and reduced dosing treatment protocols cure Trypanosoma cruzi infection in mice.Back to the future in Chagas disease: from animal models to patient cohort studies, progress in immunopathogenesis research.The chemistry and biology of trypanosomal trans-sialidases: virulence factors in Chagas disease and sleeping sickness.Dysfunctional adaptive immunity during parasitic infections Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1.Chagas disease immunogenetics: elusive markers of disease progression.Assessment of CD8(+) T cell differentiation in Trypanosoma cruzi-infected children.The Significance of Discordant Serology in Chagas Disease: Enhanced T-Cell Immunity to Trypanosoma cruzi in Serodiscordant Subjects.Specific activation of CD4- CD8- double-negative T cells by Trypanosoma cruzi-derived glycolipids induces a proinflammatory profile associated with cardiomyopathy in Chagas patients.Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico.Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease.Protective immunity against Trypanosoma cruzi.In vivo infection by Trypanosoma cruzi: The conserved FLY domain of the gp85/trans-sialidase family potentiates host infection Distinct Treatment Outcomes of Antiparasitic Therapy in -Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease

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HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

http://www.wikidata.org/entity/Q33375075

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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HLA Class I-T cell epitopes fr ...... lls in chronic Chagas disease.

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HLA Class I-T cell epitopes fr ...... lls in chronic Chagas disease.

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HLA Class I-T cell epitopes fr ...... lls in chronic Chagas disease.

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HLA Class I-T cell epitopes fr ...... lls in chronic Chagas disease.

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PLOS Neglected Tropical Diseases

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HLA Class I-T cell epitopes fr ...... lls in chronic Chagas disease.

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Alejandro H Armenti

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Carina Olivera

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D Brent Weatherly

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John Sidney

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María C Albareda

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María G Alvarez

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Miriam Postan

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Rick L Tarleton

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Susana A Laucella

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Creative Commons Attribution 2.5 Unported

P2860

The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data.

HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles.

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes

Chagas disease etiology: autoimmunity or parasite persistence?

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses.

HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism.

Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi.

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10.1371/JOURNAL.PNTD.0000288

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Alessandro Sette

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2008-09-03T00:00:00Z

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