Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.
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Activin signaling in microsatellite stable colon cancers is disrupted by a combination of genetic and epigenetic mechanisms.Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cellsExpression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutationsOn the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre miceGRG Profiles: John M. Carethers.HEREDITARY, SPORADIC AND METASTATIC COLORECTAL CANCER ARE COMMONLY DRIVEN BY SPECIFIC SPECTRUMS OF DEFECTIVE DNA MISMATCH REPAIR COMPONENTS.Rapid generation of hypomorphic mutations.Flanking nucleotide specificity for DNA mismatch repair-deficient frameshifts within activin receptor 2 (ACVR2).Both microsatellite length and sequence context determine frameshift mutation rates in defective DNA mismatch repair.Flanking sequence specificity determines coding microsatellite heteroduplex and mutation rates with defective DNA mismatch repair (MMR)Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.Production of truncated MBD4 protein by frameshift mutation in DNA mismatch repair-deficient cells enhances 5-fluorouracil sensitivity that is independent of hMLH1 status.The screening of the functional microRNA binding site SNPs in sporadic colorectal cancer genes.Microsatellite Instability Pathway and EMAST in Colorectal Cancer.
P2860
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P2860
Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@ast
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@en
type
label
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@ast
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@en
prefLabel
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@ast
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@en
P2093
P2860
P1433
P1476
Mutation rates of TGFBR2 and A ...... defective DNA mismatch repair.
@en
P2093
Claudia G Lopez
Deena Ream-Robinson
Dennis J Young
Heekyung Chung
Jeffrey K Lee
John M Carethers
Sherry C Huang
Thuy-Anh T Le
P2860
P356
10.1371/JOURNAL.PONE.0003463
P407
P577
2008-10-21T00:00:00Z