Genome-wide screen in Francisella novicida for genes required for pulmonary and systemic infection in mice
about
Live attenuated Francisella novicida vaccine protects against Francisella tularensis pulmonary challenge in rats and non-human primatesThe complex amino acid diet of Francisella in infected macrophagesComparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspeciesMetabolic network analysis-based identification of antimicrobial drug targets in category A bioterrorism agentsChitinases are negative regulators of Francisella novicida biofilmsProduction of outer membrane vesicles and outer membrane tubes by Francisella novicida.Azithromycin effectiveness against intracellular infections of Francisella.Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection modelMolecular bases of proliferation of Francisella tularensis in arthropod vectors.Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensisContributions of Francisella tularensis subsp. novicida chitinases and Sec secretion system to biofilm formation on chitin.Whole-genome sequencing reveals distinct mutational patterns in closely related laboratory and naturally propagated Francisella tularensis strainsReciprocal analysis of Francisella novicida infections of a Drosophila melanogaster model reveal host-pathogen conflicts mediated by reactive oxygen and imd-regulated innate immune responseDeciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.Identification of T-cell epitopes in Francisella tularensis using an ordered protein array of serological targets.Mining high-throughput experimental data to link gene and functionIndoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophsPivotal role of the Francisella tularensis heat-shock sigma factor RpoH.Directed screen of Francisella novicida virulence determinants using Drosophila melanogaster.Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.IglC and PdpA are important for promoting Francisella invasion and intracellular growth in epithelial cellsIdentification of essential genes in C. jejuni genome highlights hyper-variable plasticity regions.Genotype-phenotype associations in a nonmodel prokaryote.Low dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination.Identification of a novel small RNA modulating Francisella tularensis pathogenicity.Identification of Francisella novicida mutants that fail to induce prostaglandin E(2) synthesis by infected macrophages.Use of a capture-based pathogen transcript enrichment strategy for RNA-Seq analysis of the Francisella tularensis LVS transcriptome during infection of murine macrophages.Francisella tularensis metabolism and its relation to virulence.The capBCA Locus is Required for Intracellular Growth of Francisella tularensis LVS.Glycosylation of DsbA in Francisella tularensis subsp. tularensis.OGEE: an online gene essentiality database.Uncovering major genomic features of essential genes in Bacteria and a methanogenic ArchaeaComparative Transcriptional Analyses of Francisella tularensis and Francisella novicida.An expanded transposon-mutant library reveals that Vibrio fischeri δ-aminolevulinate auxotrophs can colonize Euprymna scolopesRepression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognitionThe Protease Locus of Francisella tularensis LVS Is Required for Stress Tolerance and Infection in the Mammalian Host.Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.Working toward the future: insights into Francisella tularensis pathogenesis and vaccine development.Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.
P2860
Q27323387-9808B9D3-8E85-446F-8A4D-09955B5F6486Q28080894-C7C1C33A-4190-4D55-8004-2995CE6B655BQ28475535-B575FB54-B166-4A4F-9CCC-2BF99CF74008Q28538700-A144EBEA-5E48-4E6A-BF93-B6031A4BEAE6Q28541442-5285BEC1-4327-48DE-9625-C04559E27A4DQ30417437-9BC9815E-1D4B-41AA-A1E2-7465144967A4Q30435916-D43ADEF1-41D4-43EB-981C-9283A5173120Q30863455-CDCAA58E-3F85-4F5D-82FA-EB1A5DEEEF36Q33581030-CEC8715D-40F7-4BAC-8DD4-A513F1F0DF36Q33581036-2FEFCB8A-142B-4516-BECE-182A78776CD0Q33585602-E2F7D3D6-86B7-4F35-AF20-AD7A0C300A87Q33640364-91B30762-A1B0-4586-BA84-2E184905B8E1Q33701794-CD14BCF1-ADE5-4B70-9F7D-9E111E5D0B51Q33721327-A5E14CE5-DC50-4666-828D-829EF2E3AA53Q33747324-356626CD-7409-4FC3-9F20-1BBDF8D76BD2Q33788322-F0B54C16-B21C-4010-8120-BEBAF9B5DD26Q33817768-54E89E26-8580-4EE0-96CB-1D97E7FAB8BBQ33877246-005E763C-1F05-4B38-AF2F-D66D289D4CA0Q33923017-50438D20-542E-42CA-8176-34613007A04CQ33963154-C4360954-7CC2-48A7-8625-3B090D61972FQ34018936-3B978699-F084-4A9F-A14B-0EF27B972977Q34035513-DD5A7C0D-88D8-4B82-BA8E-966BC830D11BQ34166330-67C69714-FB25-41EB-9A48-5B721E8582A0Q34204380-52ABEDA9-23AE-4278-BBAD-11B8F885EA82Q34291236-52151F3D-9353-42D0-969C-4C89BF46324FQ34359360-9CB884C8-6B15-4320-8947-95B618448490Q34583513-0CA5FA87-C121-403C-BD59-E9DE3A3BBDBDQ35025533-0642B3EA-3583-443D-9370-E6F9C84EB6C5Q35029108-8F0FE6B6-4DF5-45DA-8C43-C8C680C7435CQ35084495-F22D2299-E616-4957-B1DE-CD06C14E41B4Q35274441-0EFCFB70-0045-40A7-978B-141DD1F010C2Q35630912-E6AFFC8E-9DE5-4191-9448-3858B152E509Q35666678-9DC2ACF9-8103-4D47-A4CA-6FE22917DEDAQ36106837-13F33AB9-33AB-4F37-92F5-3E89D2C9E5DAQ36230782-472D5EBC-68BD-4D0F-9119-852EFFD3848EQ36236696-0ECFDD21-A526-4139-907B-AC7415DDCC66Q36888447-5224354A-D26C-4784-979D-79D35F9B2832Q37353316-5D54477E-8EED-4B80-AD15-7D56152CAD54Q37451520-152FE2BE-A0B4-4812-B792-D78A43F3F44DQ37488150-18A05F0A-FC1F-4F84-B0E2-1A0355C661E5
P2860
Genome-wide screen in Francisella novicida for genes required for pulmonary and systemic infection in mice
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Genome-wide screen in Francise ...... and systemic infection in mice
@ast
Genome-wide screen in Francise ...... and systemic infection in mice
@en
type
label
Genome-wide screen in Francise ...... and systemic infection in mice
@ast
Genome-wide screen in Francise ...... and systemic infection in mice
@en
prefLabel
Genome-wide screen in Francise ...... and systemic infection in mice
@ast
Genome-wide screen in Francise ...... and systemic infection in mice
@en
P2093
P2860
P356
P1476
Genome-wide screen in Francise ...... and systemic infection in mice
@en
P2093
Allison Mitchell
Colin Manoil
Larry A Gallagher
Laurence Rohmer
Mark R Pelletier
Mike Wasnick
Mitchell J Brittnacher
Petra S Kraemer
Shawn J Skerett
P2860
P304
P356
10.1128/IAI.00978-08
P407
P577
2008-10-27T00:00:00Z