Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
about
von Willebrand disease: clinical and laboratory lessons learned from the large von Willebrand disease studiesPregnancy in type 2B VWD: a case series.von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3.Congenital platelet disorders and understanding of platelet function.Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation.Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models.Porcine and canine von Willebrand factor and von Willebrand disease: hemostasis, thrombosis, and atherosclerosis studies.A genetically-engineered von Willebrand disease type 2B mouse model displays defects in hemostasis and inflammation.Von Willebrand Factor Abnormalities Studied in the Mouse Model: What We Learned about VWF Functions.The molecular genetics of von Willebrand diseasevon Willebrand disease: advances in pathogenetic understanding, diagnosis, and therapy.Advances in our understanding of the molecular basis of disorders of platelet function.von Willebrand factor: the old, the new and the unknown.Large psoas haematoma and femoral neuropathy in a patient with type 2B von Willebrand's disease.The physical spacing between the von willebrand factor d'd3- and a1- domains regulates platelet adhesion in vitro and in vivo.Abnormal von Willebrand factor secretion, factor VIII stabilization and thrombus dynamics in type 2N von Willebrand disease mice.In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W.
P2860
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P2860
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
description
2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@ast
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@en
type
label
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@ast
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@en
prefLabel
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@ast
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@en
P2093
P1433
P1476
Mutation-specific hemostatic v ...... lebrand disease substitutions.
@en
P2093
Carol Hegadorn
David Lillicrap
Jeffrey Mewburn
Kate Sponagle
Kimberly Laverty
Mia Golder
P304
P356
10.1182/BLOOD-2009-11-253120
P407
P577
2010-04-06T00:00:00Z