Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
about
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis.Molecular modeling, quantum polarized ligand docking and structure-based 3D-QSAR analysis of the imidazole series as dual AT(1) and ET(A) receptor antagonists.In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).In vitro, fluorescence-quenching and computational studies on the interaction between lipoxygenase and 5-hydroxy-3',4',7-trimethoxyflavone from Lippia nodiflora L.Exploration of potential EGFR inhibitors: a combination of pharmacophore-based virtual screening, atom-based 3D-QSAR and molecular docking analysis.
P2860
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@ast
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@en
type
label
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@ast
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@en
prefLabel
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@ast
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@en
P1476
Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues.
@en
P2093
Md Afroz Alam
Pradeep Kumar Naik
P2888
P304
P356
10.1007/S10822-008-9252-1
P577
2008-12-04T00:00:00Z