Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
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A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucoseInsights into the genetic basis of type 2 diabetesGenetic determinants of variability in glycated hemoglobin (HbA(1c)) in humans: review of recent progress and prospects for use in diabetes careAllelic polymorphism within the TAS1R3 promoter is associated with human taste sensitivity to sucrose.Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.Can data science inform environmental justice and community risk screening for type 2 diabetes?Genetic variants in eleven telomere-associated genes and the risk of incident cardio/cerebrovascular disease: The Women's Genome Health Study.Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study).Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetesRace-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III).Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathwaysMultiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians.Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID studyGenetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.Recent advances in understanding the genetic architecture of type 2 diabetesOverexpression of metabolic markers HK1 and PKM2 contributes to lymphatic metastasis and adverse prognosis in Chinese gastric cancer.Independent effect of ethnicity on glycemia in South Asians and white EuropeansAssociation Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus DevelopmentSusceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.When the blood glucose and the HbA(1c) don't match: turning uncertainty into opportunity.Proteomic analysis of energy metabolism and signal transduction in irradiated melanoma cells.A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry.Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes riskGenetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits.Clinically significant disagreement between mean blood glucose and estimated average glucose in two populations: implications for diabetes management.Biologic variability in plasma glucose, hemoglobin A1c, and advanced glycation end products associated with diabetes complications.Sequence variants in three loci influence monocyte counts and erythrocyte volume.Dominant form of congenital hyperinsulinism maps to HK1 region on 10q.A two-stage inter-rater approach for enrichment testing of variants associated with multiple traitsGenome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS).From genotype to human β cell phenotype and beyond.Zinc, pancreatic islet cell function and diabetes: new insights into an old story.Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits.Meta-analyses of the association of G6PC2 allele variants with elevated fasting glucose and type 2 diabetes.Expression patterns of three regulation enzymes in glycolysis in esophageal squamous cell carcinoma: association with survival.Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.Type 2 Diabetes Prevention: Implications of Hemoglobin A1c Genetics.
P2860
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P2860
Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Novel association of HK1 with ...... e Women's Genome Health Study.
@ast
Novel association of HK1 with ...... e Women's Genome Health Study.
@en
type
label
Novel association of HK1 with ...... e Women's Genome Health Study.
@ast
Novel association of HK1 with ...... e Women's Genome Health Study.
@en
prefLabel
Novel association of HK1 with ...... e Women's Genome Health Study.
@ast
Novel association of HK1 with ...... e Women's Genome Health Study.
@en
P2093
P2860
P1433
P1476
Novel association of HK1 with ...... e Women's Genome Health Study.
@en
P2093
Alexander N Parker
Daniel I Chasman
David M Nathan
Joseph P Miletich
Paul M Ridker
Robert Y Zee
P2860
P304
P356
10.1371/JOURNAL.PGEN.1000312
P577
2008-12-19T00:00:00Z