Expansion of the human mu-opioid receptor gene architecture: novel functional variants - Wikidata - awgldk - TriplyDB

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

http://www.wikidata.org/entity/Q33395205

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A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification.Evolution of alternative and constitutive regions of mammalian 5'UTRs.Tolerance and withdrawal from prolonged opioid use in critically ill children.Broad-spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene.Low back pain in older adults: risk factors, management options and future directions.Molecular insights into mu opioid pharmacology: From the clinic to the bench.Evolution at protein ends: major contribution of alternative transcription initiation and termination to the transcriptome and proteome diversity in mammals.ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers.OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues.Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1 Attenuation of activity in an endogenous analgesia circuit by ongoing pain in the rat Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity.Recent advances in the use of opioids for cancer pain Review of preclinical studies on treatment of mucositis and associated pain Opioids and their receptors: Are we there yet?Identification and characterization of seven new exon 11-associated splice variants of the rat μ opioid receptor gene, OPRM1.Prenatal exposure to cigarette smoke interacts with OPRM1 to modulate dietary preference for fat.Cocaine-induced suppression of saccharin intake and morphine modulation of Ca²⁺ channel currents in sensory neurons of OPRM1 A118G mice Haplotype block structure of the genomic region of the mu opioid receptor gene.The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene.Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors.Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample.Novel rank-based approaches for discovery and replication in genome-wide association studies.Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia.Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer Cortical opioid markers in schizophrenia and across postnatal development.Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1 The design and methods of genetic studies on acute and chronic postoperative pain in patients after total knee replacement Pharmacogenetic approaches to the treatment of alcohol addiction.Next-generation sequencing of human opioid receptor genes based on a custom AmpliSeq™ library and ion torrent personal genome machine Regulation and Functional Implications of Opioid Receptor Splicing in Opioid Pharmacology and HIV Pathogenesis Analgesia and central side-effects: two separate dimensions of morphine response.Gender, variation in opioid receptor genes and sensitivity to experimental pain.Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?Opioid receptor polymorphism A118G associated with clinical severity in a drug overdose population

P2860

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P2860

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

http://www.wikidata.org/entity/Q33395205

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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type

label

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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prefLabel

Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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Human Molecular Genetics

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Expansion of the human mu-opioid receptor gene architecture: novel functional variants

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Aleksey Y Ogurtsov

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Bikashkumar Mishra

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Carly Kiselycznyk

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Inna Belfer

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Inna E Tchivileva

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Josee Gauthier

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Kyoko Shibata

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Luda Diatchenko

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Margaret R Wallace

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Mitchell B Max

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P2860

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

Mfold web server for nucleic acid folding and hybridization prediction

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Recognition of unknown conserved alternatively spliced exons.

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

PAML: a program package for phylogenetic analysis by maximum likelihood

Identification of three new alternatively spliced variants of the rat mu opioid receptor gene: dissociation of affinity and efficacy

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1037-1051

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10.1093/HMG/DDN439

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6

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18

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Svetlana A. Shabalina

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2008-12-22T00:00:00Z

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23685275

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19103668

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2649019

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