IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. - Wikidata - awgldk - TriplyDB

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

http://www.wikidata.org/entity/Q33396971

about

Revealing the genetic basis of multiple sclerosis: are we there yet?Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity Daclizumab therapy for multiple sclerosis Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci Type 1 diabetes: translating mechanistic observations into effective clinical outcomes Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.Plasma Levels of Soluble Interleukin-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping Pervasive sharing of genetic effects in autoimmune disease.Genetics of type 1 diabetes: what's next?Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.The type I diabetes association of the IL2RA locus.Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.Family studies of type 1 diabetes reveal additive and epistatic effects between MGAT1 and three other polymorphisms No evidence of association of the rare nsSNP rs35667974 in IFIH1 with multiple sclerosis.Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis.Genetic burden in multiple sclerosis families Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.BCL6 controls Th9 cell development by repressing Il9 transcription.Interleukin 2 receptor α gene polymorphism and risk of multiple sclerosis: a meta-analysis.Distinct genetic control of autoimmune neuropathy and diabetes in the non-obese diabetic background.Statistical testing of shared genetic control for potentially related traits.Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis.Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.Progress and promise of genome-wide association studies for human complex trait genetics An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition.Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.Multiple autoimmune-associated variants confer decreased IL-2R signaling in CD4+ CD25(hi) T cells of type 1 diabetic and multiple sclerosis patients Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game Associations of Independent IL2RA Gene Variants with Intermediate Uveitis Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions.Interleukin-2, Interleukin-7, T cell-mediated autoimmunity, and N-glycosylation.Genetic determinants of risk and progression in multiple sclerosis.Hypomorphic MGAT5 polymorphisms promote multiple sclerosis cooperatively with MGAT1 and interleukin-2 and 7 receptor variants.Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.IL2RA is associated with persistence of rheumatoid arthritis.

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P2860

IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production.

http://www.wikidata.org/entity/Q33396971

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2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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Brian Healy

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Christopher E Lowe

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Cristin Aubin

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David E Anderson

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International Multiple Sclerosis Genetics Consortium

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Jason Cooper

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Jorge R Oksenberg

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Kate Downes

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P2860

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Haploview: analysis and visualization of LD and haplotype maps

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Protein tyrosine phosphatase PTPN22 in human autoimmunity

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

Risk alleles for multiple sclerosis identified by a genomewide study

Population structure, differential bias and genomic control in a large-scale, case-control association study

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