Modeling and molecular dynamics of HPA-1a and -1b polymorphisms: effects on the structure of the β3 subunit of the αIIbβ3 integrin.

Modeling and molecular dynamics of HPA-1a and -1b polymorphisms: effects on the structure of the β3 subunit of the αIIbβ3 integrin.

Item
http://www.wikidata.org/entity/Q33404386
Protein flexibility in the light of structural alphabetsDetecting protein candidate fragments using a structural alphabet profile comparison approach.αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia.Pro32Pro33 mutations in the integrin β3 PSI domain result in αIIbβ3 priming and enhanced adhesion: reversal of the hypercoagulability phenotype by the Src inhibitor SKI-606.Molecular dynamics analysis of a novel β3 Pro189Ser mutation in a patient with glanzmann thrombasthenia differentially affecting αIIbβ3 and αvβ3 expression.Cis-trans isomerization of omega dihedrals in proteins.In silico analysis of Glanzmann variants of Calf-1 domain of αIIbβ3 integrin revealed dynamic allosteric effect.PBxplore: a tool to analyze local protein structure and deformability with Protein Blocks.The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain.Structural insights into the extra cellular segment of integrinβ5 and molecular interaction studies.Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome.The human platelet antigen-1b variant of αIIbβ3 allosterically shifts the dynamic conformational equilibrium of this integrin toward the active state.
P2860

Modeling and molecular dynamics of HPA-1a and -1b polymorphisms: effects on the structure of the β3 subunit of the αIIbβ3 integrin.

Item
http://www.wikidata.org/entity/Q33404386
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
@ast
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
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type
label
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
@ast
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
@en
prefLabel
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
@ast
Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
@en
P1433
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P2860
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P5875
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Modeling and molecular dynamic ...... ubunit of the αIIbβ3 integrin.
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P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0047304
P407
P433
P478
P50
P577
P5875
P698
P921
P932