PDK1 regulates platelet activation and arterial thrombosis.
about
AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation.Deubiquitinases Modulate Platelet Proteome Ubiquitination, Aggregation, and Thrombosis.Modulation of platelet activation and thrombus formation using a pan-PI3K inhibitor S14161.Paired immunoglobulin-like receptor B regulates platelet activation.Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.Identification of a novel platelet antagonist that binds to CLEC-2 and suppresses podoplanin-induced platelet aggregation and cancer metastasisThrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM PatientsThe serum- & glucocorticoid-inducible kinase in the regulation of platelet function.Integrin αIIbβ3 outside-in signaling.Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia.Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.Conditional PDK1 Ablation Promotes Epidermal and T-Cell-Mediated Dysfunctions Leading to Inflammatory Skin Disease.Pharmacological inhibition of S6K1 facilitates platelet activation by enhancing Akt phosphorylation.Atractylodes lactone compounds inhibit platelet activation.Psoralen and Ultraviolet A Light Treatment Directly Affects Phosphatidylinositol 3-Kinase Signal Transduction by Altering Plasma Membrane Packing.Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway.Integrated microRNA-mRNA analysis of coronary artery disease.Platelet Signaling Pathways and New Inhibitors.Insulin augments serotonin-induced contraction via activation of the IR/PI3K/PDK1 pathway in the rat carotid artery.PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
P2860
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P2860
PDK1 regulates platelet activation and arterial thrombosis.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
PDK1 regulates platelet activation and arterial thrombosis.
@ast
PDK1 regulates platelet activation and arterial thrombosis.
@en
type
label
PDK1 regulates platelet activation and arterial thrombosis.
@ast
PDK1 regulates platelet activation and arterial thrombosis.
@en
prefLabel
PDK1 regulates platelet activation and arterial thrombosis.
@ast
PDK1 regulates platelet activation and arterial thrombosis.
@en
P2093
P1433
P1476
PDK1 regulates platelet activation and arterial thrombosis.
@en
P2093
Junling Liu
Kemin Wang
Xinping Luo
Yanhua Wang
Zhongzhou Yang
P304
P356
10.1182/BLOOD-2012-10-461897
P407
P577
2013-02-26T00:00:00Z