A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution
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Firefly Luciferase in Chemical Biology: A Compendium of Inhibitors, Mechanistic Evaluation of Chemotypes, and Suggested Use As a ReporterTitration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase InhibitorsEngineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrateA novel method for mining highly imbalanced high-throughput screening data in PubChem.Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinaseComparison of bioluminescent kinase assays using substrate depletion and product formation.A high-throughput 1,536-well luminescence assay for glutathione S-transferase activity.Optimized high-throughput screen for hepatitis C virus translation inhibitors.Total Synthesis and Biological Studies of TMC-205 and Analogues as Anticancer Agents and Activators of SV40 Promoter.Illuminating insights into firefly luciferase and other bioluminescent reporters used in chemical biologyA homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.Discovery, synthesis, and biological evaluation of novel SMN protein modulators.Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase, and PI5P4Kα Lipid Kinase.Quantitative High-Throughput Screening Using a Coincidence Reporter Biocircuit.Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells.The nuclear factor κB inhibitor (E)-2-fluoro-4'-methoxystilbene inhibits firefly luciferase.Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors.Comparison of luminescence ADP production assay and radiometric scintillation proximity assay for Cdc7 kinase.Robust light emission from cyclic alkylaminoluciferin substrates for firefly luciferase.Prediction of luciferase inhibitors by the high-performance MIEC-GBDT approach based on interaction energetic patterns.Discovery of a series of 2-phenylnaphthalenes as firefly luciferase inhibitorsSynthesis and biological evaluation of a series of aryl triazoles as firefly luciferase inhibitors
P2860
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P2860
A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
A basis for reduced chemical l ...... tained from directed evolution
@ast
A basis for reduced chemical l ...... tained from directed evolution
@en
type
label
A basis for reduced chemical l ...... tained from directed evolution
@ast
A basis for reduced chemical l ...... tained from directed evolution
@en
prefLabel
A basis for reduced chemical l ...... tained from directed evolution
@ast
A basis for reduced chemical l ...... tained from directed evolution
@en
P2093
P2860
P50
P356
P1476
A basis for reduced chemical l ...... tained from directed evolution
@en
P2093
Craig J Thomas
Daniel Langevin
Douglas S Auld
Ganesha Rai
James Inglese
Marc Landsman
Ya-Qin Zhang
P2860
P304
P356
10.1021/JM8014525
P407
P577
2009-03-01T00:00:00Z