Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation
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Underground Adaptation to a Hostile Environment: Acute Myeloid Leukemia vs. Natural Killer CellsTargeting the leukemia-stroma interaction in acute myeloid leukemia: rationale and latest evidencePlaying musical chairs with bone marrow transplantation to eliminate leukemia stem cellsIn vivo longitudinal visualization of bone marrow engraftment process in mouse calvaria using two-photon microscopy.Translocation (8;21) acute myeloid leukemia presenting as severe aplastic anemia.Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia.Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue.Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation.Digitalization of a non-irradiated acute myeloid leukemia model.Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML.Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.Relevance of leukemic stem cells in acute myeloid leukemia: heterogeneity and influence on disease monitoring, prognosis and treatment design.An extensive pharmacokinetic, metabolic and toxicological review of elderly patients under intensive chemotherapy for acute myeloid leukemia.Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.Clonal selection and therapy resistance in acute leukaemias: mathematical modelling explains different proliferation patterns at diagnosis and relapse.Therapeutically targeting SELF-reinforcing leukemic niches in acute myeloid leukemia: A worthy endeavor?Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced MicroenvironmentReduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia.On the potential role of DNMT1 in acute myeloid leukemia and myelodysplastic syndromes: not another mutated epigenetic driver.Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice.AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB.Hyper-recovery of platelets after induction therapy is a predictor of relapse-free survival in acute myeloid leukemia.Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia.Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.System modeling reveals the molecular mechanisms of HSC cell cycle alteration mediated by Maff and Egr3 under leukemia.Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow.Pretreatment platelet count predicts survival outcome of patients with de novo non-M3 acute myeloid leukemia.Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche.Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space.High frequency of CD34+CD38-/low immature leukemia cells is correlated with unfavorable prognosis in acute myeloid leukemia.Underlying undiagnosed inherited marrow failure syndromes among children with cancer.
P2860
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P2860
Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Acute myeloid leukemia does no ...... impeding their differentiation
@ast
Acute myeloid leukemia does no ...... impeding their differentiation
@en
type
label
Acute myeloid leukemia does no ...... impeding their differentiation
@ast
Acute myeloid leukemia does no ...... impeding their differentiation
@en
prefLabel
Acute myeloid leukemia does no ...... impeding their differentiation
@ast
Acute myeloid leukemia does no ...... impeding their differentiation
@en
P2093
P2860
P356
P1476
Acute myeloid leukemia does no ...... impeding their differentiation
@en
P2093
David C Taussig
Debra Lillington
Dominique Bonnet
Farideh Miraki-Moud
Fernando Anjos-Afonso
Guglielmo Rosignoli
Heather Oakervee
Jamie Cavenagh
Jeff K Davies
John G Gribben
P2860
P304
13576-13581
P356
10.1073/PNAS.1301891110
P407
P577
2013-07-30T00:00:00Z