A phase I trial of imetelstat in children with refractory or recurrent solid tumors: a Children's Oncology Group Phase I Consortium Study (ADVL1112).

A phase I trial of imetelstat in children with refractory or recurrent solid tumors: a Children's Oncology Group Phase I Consortium Study (ADVL1112).

Item
http://www.wikidata.org/entity/Q33410758
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsA molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study.Imetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis.Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.Perifosine as a potential novel anti-telomerase therapy.Telomere maintenance in soft tissue sarcomasInvestigational therapies for Ewing sarcoma: a search without a clear finding.Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors.A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.Quantitative analysis of imetelstat in plasma with LC-MS/MS using solid-phase or hybridization extraction.Targeted Tumor Therapy Remixed-An Update on the Use of Small-Molecule Drugs in Combination Therapies.Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cellsImetelstat, a telomerase inhibitor, is capable of depleting myelofibrosis stem and progenitor cells
P2860

A phase I trial of imetelstat in children with refractory or recurrent solid tumors: a Children's Oncology Group Phase I Consortium Study (ADVL1112).

Item
http://www.wikidata.org/entity/Q33410758
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@ast
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@en
type
label
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@ast
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@en
prefLabel
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@ast
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
A phase I trial of imetelstat ...... I Consortium Study (ADVL1112).
@en
P2093
P2860
P304
P31
P356
10.1158/1078-0432.CCR-13-1117
P407
P433
P478
P50
P577
P698
P921
P932