Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin - Wikidata - awgldk - TriplyDB

Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin

Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin

http://www.wikidata.org/entity/Q33415491

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Nail Psoriasis: A Review of Treatment Options The new insight into the role of antimicrobial proteins-alarmins in the immunopathogenesis of psoriasis Determining multiallelic complex copy number and sequence variation from high coverage exome sequencing data Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease.Human β-Defensin 2 in Primary Sclerosing Cholangitis.Copy number variation of the beta defensin gene cluster on chromosome 8p influences the bacterial microbiota within the nasopharynx of otitis-prone children.Angiogenesis QTL on Mouse Chromosome 8 Colocalizes with Differential β-Defensin Expression.In vivo expression of antimicrobial peptides in atopic dermatitis.Clinical application of human β-defensin and CD14 gene polymorphism in evaluating the status of chronic inflammation Association of Higher Defensin β-4 Genomic Copy Numbers with Behçet's Disease in Iraqi Patients.Update on psoriasis immunopathogenesis and targeted immunotherapy.Copy Number Variation within Human β-Defensin Gene Cluster Influences Progression to AIDS in the Multicenter AIDS Cohort Study.CCR6 as a possible therapeutic target in psoriasis.Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes.Psoriasis: from pathogenesis to novel therapeutic approaches.β-Defensins: multifunctional modulators of infection, inflammation and more?Ultraviolet radiation-induced upregulation of antimicrobial proteins in health and disease.Chemokine receptors in psoriasis.Human gene copy number variation and infectious disease.An evolutionary history of defensins: a role for copy number variation in maximizing host innate and adaptive immune responses.Skin equivalents: skin from reconstructions as models to study skin development and diseases.In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research.Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.Defensin gene variation and HIV/AIDS: a comprehensive perspective needed.Biomarkers and personalized medicine: current status and further perspectives with special focus on dermatology.Secukinumab: A Review in Psoriatic Arthritis.Lessons to be learned from serum biomarkers in psoriasis and IBD - the potential role in SpA.Human β-defensin 3 increases the TLR9-dependent response to bacterial DNA No Evidence for Association of β-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS.The skin surface as antimicrobial barrier: present concepts and future outlooks.Serum levels of antimicrobial peptides and proteins do not correlate with psoriasis severity and are increased after treatment with fumaric acid esters.IL-17A plays a central role in the expression of psoriasis signature genes through the induction of IκB-ζ in keratinocytes.A worldwide analysis of beta-defensin copy number variation suggests recent selection of a high-expressing DEFB103 gene copy in East Asia.Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study.Population Pharmacokinetic Modeling of Secukinumab in Patients With Moderate to Severe Psoriasis.Endogenous animal toxin-like human β-defensin 2 inhibits own K(+) channels through interaction with channel extracellular pore region.Serum inflammatory biomarkers fail to identify early axial spondyloarthritis: results from the SpondyloArthritis Caught Early (SPACE) cohort Human β-defensin-2 as a marker for disease severity and skin barrier properties in atopic dermatitis.β-defensin genomic copy number is associated with HIV load and immune reconstitution in sub-saharan Africans.Beta-defensins and Crohn's disease: confusion from counting copies.

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P2860

Beta-defensin-2 protein is a serum biomarker for disease activity in psoriasis and reaches biologically relevant concentrations in lesional skin

http://www.wikidata.org/entity/Q33415491

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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P2860

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells

Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster.

Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung

A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Defensins: antimicrobial peptides of innate immunity

A peptide antibiotic from human skin

Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

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