Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition - Wikidata - awgldk - TriplyDB

Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition

Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition

http://www.wikidata.org/entity/Q33419829

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Cerebral malaria: mysteries at the blood-brain barrier Coma associated with microscopy-diagnosed Plasmodium vivax: a prospective study in Papua, Indonesia ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings.Severe dengue is associated with consumption of von Willebrand factor and its cleaving enzyme ADAMTS-13 VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.ADAMTS13 and von Willebrand factor interactions.A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria Pathophysiology of Pediatric Multiple Organ Dysfunction Syndrome.Platelets and infections in the resource-limited countries with a focus on malaria and viral haemorrhagic fevers.Elevated plasma von Willebrand factor and propeptide levels in Malawian children with malaria.Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF.Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation.Association of ADAMTS13 polymorphism with cerebral malaria.Angiopoietin-2 levels are associated with retinopathy and predict mortality in Malawian children with cerebral malaria: a retrospective case-control study*Preserved Expression of mRNA Coding von Willebrand Factor-Cleaving Protease ADAMTS13 by Selenite and Activated Protein C.Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura.Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding.Cytoadherence and severe malaria.Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial.Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice.Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children Evidence of Endothelial Activation in Asymptomatic Plasmodium falciparum Parasitemia and Effect of Blood Group on Levels of von Willebrand Factor in Malaria.Structure-function and regulation of ADAMTS-13 protease.Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis.Biomarkers of endothelial activation/dysfunction in infectious diseases.Malaria: modification of the red blood cell and consequences in the human host.Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria.Cerebral malaria pathogenesis: revisiting parasite and host contributions.Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence.Immunobiology of Plasmodium in liver and brain.The mechanistic, diagnostic and prognostic utility of biomarkers in severe malaria.The immunological balance between host and parasite in malaria.Cerebral malaria--clinical manifestations and pathogenesis.IL-1β down-regulates ADAMTS-13 mRNA expression in cells of the central nervous system.

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P2860

Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition

http://www.wikidata.org/entity/Q33419829

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2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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JOURNAL.PPAT.1000349

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Severe Plasmodium falciparum m ...... timers and ADAMTS13 inhibition

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Bas de Laat

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Cynthia Donkor

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Deirdre Larkin

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George E Grau

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James Bunn

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Jan A van Mourik

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Roger J S Preston

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Virginie Terraube

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P2860

Biochemistry and genetics of von Willebrand factor

Inducible secretion of large, biologically potent von Willebrand factor multimers

Molecules on the surface of the Plasmodium falciparum infected erythrocyte and their role in malaria pathogenesis and immune evasion

ADAMTS13 and TTP

ADAMTS13 turns 3

von Willebrand factor propeptide in vascular disorders: A tool to distinguish between acute and chronic endothelial cell perturbation.

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura.

ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions.

Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin.

Acquired ADAMTS-13 deficiency in pediatric patients with severe sepsis.

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e1000349

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scholarly article

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10.1371/JOURNAL.PPAT.1000349

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3

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5

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Alister G Craig

P.vincent Jenkins

James S O'Donnell

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2009-03-20T00:00:00Z

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24214243

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19300493

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Plasmodium falciparum

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2652105

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