A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
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Telomere and Telomerase Therapeutics in CancerTherapeutic approaches in myelofibrosis and myelodysplastic/myeloproliferative overlap syndromesEvolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative NeoplasmsMolecular correlates of anemia in primary myelofibrosis: a significant and independent association with U2AF1 mutations.Management of lower-risk myelodysplastic syndromes without del5q: current approach and future trends.A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study.Imetelstat, a telomerase inhibitor, differentially affects normal and malignant megakaryopoiesis.Polycythemia Vera Management and Challenges in the Community Health Setting.Outcome of patients treated for myelodysplastic syndromes without deletion 5q after failure of lenalidomide therapyFibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis.New Strategies in Myeloproliferative Neoplasms: The Evolving Genetic and Therapeutic Landscape.Role of Telomeres and Telomerase in Aging and Cancer.Ruxolitinib therapy and telomere length in myelofibrosis.Targeted depletion of PIK3R2 induces regression of lung squamous cell carcinomaSocial Media and Myeloproliferative Neoplasms (MPN)--Focus on Twitter and the Development of a Disease-specific Community: #MPNSM.What Do Molecular Tests Add to Prognostic Stratification in MF: Is It Time to Add These to Our Clinical Practice?Myeloproliferative neoplasms: A decade of discoveries and treatment advances.Interferon-alpha for the therapy of myeloproliferative neoplasms: targeting the malignant clone.The evolution and clinical relevance of prognostic classification systems in myelofibrosis.Epigenetic landscape of the TERT promoter: a potential biomarker for high risk AML/MDS.Targeting telomerase with radiolabeled inhibitors.Understanding TERT Promoter Mutations: A Common Path to Immortality.Should we be treating lower risk myelofibrosis patients with a JAK2 inhibitor?Blast-phase myeloproliferative neoplasms: risk factors and treatment approaches.Contemporary insights into the pathogenesis and treatment of chronic myeloproliferative neoplasms.Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular disease.New strategies in myelofibrosis: the evolving paradigm of disease pathogenesis, prognostication and treatment.Primary myelofibrosis and its targeted therapy.Investigational histone deacetylase inhibitors (HDACi) in myeloproliferative neoplasms.Myelofibrosis: an update on drug therapy in 2016.Primary myelofibrosis: 2017 update on diagnosis, risk-stratification, and management.The role of the extracellular matrix in primary myelofibrosis.Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis (RARS-T): 2017 update on diagnosis, risk-stratification, and management.Telomere-driven diseases and telomere-targeting therapies.Management of myelofibrosis: JAK inhibition and beyond.Splicing factor mutations in MDS RARS and MDS/MPN-RS-T.Developing Cures: Targeting Ontogenesis in Cancer.Anti-thymocyte globulin-induced hyperbilirubinemia in patients with myelofibrosis undergoing allogeneic hematopoietic cell transplantation.Telomere Transcripts Target Telomerase in Human Cancer Cells.Human TERT promoter mutation enables survival advantage from MGMT promoter methylation in IDH1 wild-type primary glioblastoma treated by standard chemoradiotherapy.
P2860
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P2860
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
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2015 nî lūn-bûn
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2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@ast
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@en
type
label
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@ast
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@en
prefLabel
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@ast
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@en
P2093
P356
P1476
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
@en
P2093
Animesh Pardanani
Christy M Finke
Curtis A Hanson
Darci L Zblewski
Emnet Wassie
Kebede H Begna
Lauren Schimek
Mrinal M Patnaik
Naseema Gangat
Rebecca R Laborde
P304
P356
10.1056/NEJMOA1310523
P407
P577
2015-09-01T00:00:00Z