Biomechanical thresholds regulate inflammation through the NF-kappaB pathway: experiments and modeling. - Wikidata - awgldk - TriplyDB

Biomechanical thresholds regulate inflammation through the NF-kappaB pathway: experiments and modeling.

Biomechanical thresholds regulate inflammation through the NF-kappaB pathway: experiments and modeling.

http://www.wikidata.org/entity/Q33430814

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From tissue mechanics to transcription factors.Transcription factor regulation by mechanical stress Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis Telomere Length, Long-Term Black Carbon Exposure, and Cognitive Function in a Cohort of Older Men: The VA Normative Aging Study Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis.Gene expression responses to mechanical stimulation of mesenchymal stem cells seeded on calcium phosphate cement Characterization of a model of an arteriovenous fistula in the rat: the effect of L-NAME Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.Knee loading reduces MMP13 activity in the mouse cartilage.Emerging targets in osteoarthritis therapy.Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation.Do mouse models reflect the diversity of osteoarthritis in humans?Exercise-driven metabolic pathways in healthy cartilage.A novel device to stretch multiple tissue samples with variable patterns: application for mRNA regulation in tissue-engineered constructs.Moderate joint loading reduces degenerative actions of matrix metalloproteinases in the articular cartilage of mouse ulnae.Mechanosignaling in bone health, trauma and inflammation.Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis.Functions of nuclear factor kappaB in bone.Mechanical loading: bone remodeling and cartilage maintenance.Transcriptional modulation by VIP: a rational target against inflammatory disease.A new strategy to tackle severe knee osteoarthritis: Combination of intra-articular and intraosseous injections of Platelet Rich Plasma.P120 catenin attenuates lipopolysaccharide-induced blood-brain barrier dysfunction and inflammatory responses in human brain microvascular endothelial cells.Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination.Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB.Risk factor-dependent dynamics of atopic dermatitis: modelling multi-scale regulation of epithelium homeostasis.Mechanical loading: potential preventive and therapeutic strategy for osteoarthritis.Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor.Shifting HIFs in osteoarthritis.Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro.Magnitude-dependent and inversely-related osteogenic/chondrogenic differentiation of human mesenchymal stem cells under dynamic compressive strain.Calcium-phosphate complex increased during subchondral bone remodeling affects earlystage osteoarthritis.Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage.Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis.

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Biomechanical thresholds regulate inflammation through the NF-kappaB pathway: experiments and modeling.

http://www.wikidata.org/entity/Q33430814

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Biomechanical thresholds regul ...... way: experiments and modeling.

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Baltazar D Aguda

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Bjoern Rath

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Jin Nam

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Sudha Agarwal

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P2860

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes

Tensegrity: the architectural basis of cellular mechanotransduction.

Mechanical aspects of cell shape regulation and signaling.

Therapeutic exercise for people with osteoarthritis of the hip or knee. A systematic review.

Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells.

Sports, joint injury, and posttraumatic osteoarthritis.

Compressive forces induce osteogenic gene expression in calvarial osteoblasts.

Transcriptional regulation via the NF-kappaB signaling module.

Anti-inflammatory effects of continuous passive motion on meniscal fibrocartilage.

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