about
Tuning the dials of Synthetic BiologyComputational biology of RNA interactionsParts plus pipes: synthetic biology approaches to metabolic engineeringProgrammed evolution for optimization of orthogonal metabolic output in bacteriaThree-dimensionally designed protein-responsive RNA devices for cell signaling regulationAutomatic design of digital synthetic gene circuitsDesign principles for ligand-sensing, conformation-switching ribozymes.Dynamically reshaping signaling networks to program cell fate via genetic controllersGenetic control of mammalian T-cell proliferation with synthetic RNA regulatory systemsAntagonistic control of a dual-input mammalian gene switch by food additives.Dynamic energy landscapes of riboswitches help interpret conformational rearrangements and function.Gene regulation by riboswitches with and without negative feedback loop.A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity.Optimizing pentose utilization in yeast: the need for novel tools and approaches.Assembly and activation of a kinase ribozymeDesign of small molecule-responsive microRNAs based on structural requirements for Drosha processing.Analysis of operating principles with S-system models.Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules.A family of synthetic riboswitches adopts a kinetic trapping mechanism.Optimization of a whole-cell biocatalyst by employing genetically encoded product sensors inside nanolitre reactors.High-throughput cellular RNA device engineering.In Vitro Screening and in Silico Modeling of RNA-Based Gene Expression Control.Synthetic RNA switches as a tool for temporal and spatial control over gene expression.A versatile cis-blocking and trans-activation strategy for ribozyme characterization.Twins, quadruplexes, and more: functional aspects of native and engineered RNA self-assembly in vivoKinetics of allosteric transitions in S-adenosylmethionine riboswitch are accurately predicted from the folding landscape.Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites.Engineering biological systems with synthetic RNA molecules.Synthetic biology: advancing the design of diverse genetic systemsDesign and implementation of adoptive therapy with chimeric antigen receptor-modified T cells.Automated physics-based design of synthetic riboswitches from diverse RNA aptamersFacile characterization of aptamer kinetic and equilibrium binding properties using surface plasmon resonance.De novo design of a synthetic riboswitch that regulates transcription termination.Synthetic Botany.Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches.Ribo-attenuators: novel elements for reliable and modular riboswitch engineeringDesign of nucleic acid strands with long low-barrier folding pathways.Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range.Synthetic gene circuits for metabolic control: design trade-offs and constraints.A quantitative framework for the forward design of synthetic miRNA circuits.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Design principles for riboswitch function.
@ast
Design principles for riboswitch function.
@en
type
label
Design principles for riboswitch function.
@ast
Design principles for riboswitch function.
@en
prefLabel
Design principles for riboswitch function.
@ast
Design principles for riboswitch function.
@en
P2860
P1476
Design principles for riboswitch function.
@en
P2093
Christina D Smolke
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000363
P577
2009-04-17T00:00:00Z