Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry.
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Role of αA-crystallin-derived αA66-80 peptide in guinea pig lens crystallin aggregation and insolubilization.αA-crystallin peptide SDRDKFVIFLDVKHF accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregationAnalysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research.In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallinA method to prevent protein delocalization in imaging mass spectrometry of non-adherent tissues: application to small vertebrate lens imaging.Spatially-directed protein identification from tissue sections by top-down LC-MS/MS with electron transfer dissociation.Novel fatty acid acylation of lens integral membrane protein aquaporin-0.Mass spectrometric imaging for biomedical tissue analysisTissue localization and solubilities of αA-crystallin and its numerous C-terminal truncation products in pre- and postcataractous ICR/f rat lensesElectron tomography of fiber cell cytoplasm and dense cores of multilamellar bodies from human age-related nuclear cataracts.Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry.Spatial distribution of glycerophospholipids in the ocular lensImaging of intact tissue sections: moving beyond the microscopeFeasibility of depth profiling of animal tissue by ultrashort pulse laser ablationLipid imaging by mass spectrometry - a review.MALDI mass spectrometric imaging based identification of clinically relevant signals in prostate cancer using large-scale tissue microarrays.High spatial resolution imaging mass spectrometry of human optic nerve lipids and proteins.Imaging phosphorylated peptide distribution in human lens by MALDI MS.Understanding the α-crystallin cell membrane conjunction.Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina degenerations.High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue.Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging.MALDI imaging mass spectrometry reveals multiple clinically relevant masses in colorectal cancer using large-scale tissue microarrays.Advances in MALDI imaging mass spectrometry of proteins in cardiac tissue, including the heart valve.Degradation of an old human protein: age-dependent cleavage of γS-crystallin generates a peptide that binds to cell membranesProfiling of lens protease involved in generation of αA-66-80 crystallin peptide using an internally quenched protease substrateComparative proteomic analysis identifies age-dependent increases in the abundance of specific proteins after deletion of the small heat shock proteins αA- and αB-crystallin.The αA66-80 peptide interacts with soluble α-crystallin and induces its aggregation and precipitation: a contribution to age-related cataract formation.Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent αA(ins)-Crystallin Encode Activated ChaperonesLens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase.Old proteins and the Achilles heel of mass spectrometry. The role of proteomics in the etiology of human cataract.Regulation of αA- and αB-crystallins via phosphorylation in cellular homeostasis.The etiology of human age-related cataract. Proteins don't last foreverSmall molecules, both dietary and endogenous, influence the onset of lens cataracts.Quantitative proteomics analysis by iTRAQ in human nuclear cataracts of different ages and normal lens nuclei.Ultrastructural analysis of the human lens fiber cell remodeling zone and the initiation of cellular compaction.Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.Oligomerization with wt αA- and αB-crystallins reduces proteasome-mediated degradation of C-terminally truncated αA-crystallin.High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry.Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas.
P2860
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P2860
Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@ast
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@en
type
label
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@ast
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@en
prefLabel
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@ast
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@en
P2860
P356
P1476
Age-related changes in the spa ...... LDI imaging mass spectrometry.
@en
P2093
Kevin L Schey
P2860
P304
P356
10.1167/IOVS.09-3522
P407
P50
P577
2009-04-22T00:00:00Z