Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors.
about
miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling.Targeting MicroRNAs in Cancer Gene Therapy.Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities.A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis.EMT: Present and future in clinical oncology.The Role of miRNAs in Angiogenesis, Invasion and Metabolism and Their Therapeutic Implications in Gliomas.The Role and Molecular Mechanism of Non-Coding RNAs in Pathological Cardiac Remodeling.miRNAs: micro-managers of anticancer combination therapies.MicroRNAs in gynecological cancers: Small molecules with big implications.The role of microRNAs in colorectal liver metastasis: Important participants and potential clinical significances.MicroRNA-Directed Neuronal Reprogramming as a Therapeutic Strategy for Neurological Diseases.Targeting MicroRNAs in Prostate Cancer Radiotherapy.Significance of microRNAs in Androgen Signaling and Prostate Cancer Progression.The Clinical Application of MicroRNAs in Infectious DiseaseMicroRNA-34a: A Versatile Regulator of Myriads of Targets in Different Cancers.Small RNAs May Answer Big Questions in Mental Illness.Alternative mechanisms of miR-34a regulation in cancer.The role of miRNA and lncRNA in gastric cancer.Targeting microRNA to improve diagnostic and therapeutic approaches for malignant mesothelioma.N-AC-l-Leu-PEI-mediated miR-34a delivery improves osteogenic differentiation under orthodontic force.miR-34a expression in human breast cancer is associated with drug resistance.Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment.MiR-34a regulates the invasive capacity of canine osteosarcoma cell lines.microRNAs and Acute Myeloid Leukemia Chemoresistance: A Mechanistic Overview.RNA interference-based therapy and its delivery systems.Diagnostic and therapeutic applications of miRNA-based strategies to cancer immunotherapy.Using Genome Sequence to Enable the Design of Medicines and Chemical Probes.Aberrant miRNA promoter methylation and EMT-involving miRNAs in breast cancer metastasis: Diagnosis and therapeutic implications.Targeting tumor microenvironment to curb chemoresistance via novel drug delivery strategies.Targeting the lipid metabolic axis ACSL/SCD in colorectal cancer progression by therapeutic miRNAs: miR-19b-1 role.Searching for new biomarkers in ovarian cancer patients: Rationale and design of a retrospective study under the Mermaid III project.Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment.Hiding in Plain Sight: Rediscovering the Importance of Noncoding RNA in Human Malignancy.Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy.Expression of miR-34a in T-Cells Infected by Human T-Lymphotropic Virus 1.Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript.Modulation of intracellular calcium signaling by microRNA-34a-5pA General Overview on Non-coding RNA-Based Diagnostic and Therapeutic Approaches for Liver Diseases
P2860
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P2860
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors.
description
2016 nî lūn-bûn
@nan
2016 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@ast
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@en
type
label
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@ast
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@en
prefLabel
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@ast
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@en
P2093
P2860
P1476
Phase I study of MRX34, a lipo ...... ts with advanced solid tumors.
@en
P2093
Andreas G Bader
Andrew J Brenner
David S Hong
Jasgit Sachdev
Jay Stoudemire
Mitesh Borad
Muhammad S Beg
Susan Smith
Yoon-Koo Kang
P2860
P2888
P304
P356
10.1007/S10637-016-0407-Y
P577
2016-12-05T00:00:00Z
P6179
1030443771