An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis
about
Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agentmiR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivoDevelopment and validation of an automated high-throughput system for zebrafish in vivo screeningsHeat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidneyLabel-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopyApplications of chemogenomic library screening in drug discoveryA transgenic Xenopus laevis reporter model to study lymphangiogenesis.Heterocyclic aminoparthenolide derivatives modulate G(2)-M cell cycle progression during Xenopus oocyte maturation.Targeting lymphatic vessel functions through tyrosine kinases.A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development.Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesisLabel-free real-time imaging of myelination in the Xenopus laevis tadpole by in vivo stimulated Raman scattering microscopy.Purines as potential morphogens during embryonic development.Activation of the epidermal growth factor receptor promotes lymphangiogenesis in the skin.Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros.Mechanisms of lymphatic metastasis.Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell.Xenopus white papers and resources: folding functional genomics and genetics into the frog.Xenopus: an ideal system for chemical genetics.Synthetic molecules: helping to unravel plant signal transduction.Using frogs faces to dissect the mechanisms underlying human orofacial defects.TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models.Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts.Using Xenopus to understand human disease and developmental disorders.Cell and small animal models for phenotypic drug discovery.High-throughput identification of small molecules that affect human embryonic vascular development.High-content analysis to leverage a robust phenotypic profiling approach to vascular modulation.Pharmacological manipulation of blood and lymphatic vascularization in ex vivo-cultured mouse embryos.Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors.
P2860
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P2860
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@ast
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@en
type
label
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@ast
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@en
prefLabel
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@ast
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@en
P2093
P2860
P1433
P1476
An in vivo chemical library sc ...... ogenesis and lymphangiogenesis
@en
P2093
André W Brändli
Nadja E Bänziger-Tobler
Roland E Kälin
P2860
P304
P356
10.1182/BLOOD-2009-03-211771
P407
P577
2009-05-28T00:00:00Z