STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
about
Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer modelIFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damageInterferons as inducers of apoptosis in malignant cellsNovel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive reviewThe efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunityPeripheral immune cell gene expression changes in advanced non-small cell lung cancer patients treated with first line combination chemotherapyExpression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific mannerHigh STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer.DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cellsInterferons and their stimulated genes in the tumor microenvironmentExploring molecular links between lymph node invasion and cancer prognosis in human breast cancer.Zoledronic acid sensitizes renal cell carcinoma cells to radiation by downregulating STAT1Non-invasive, simultaneous quantification of vascular oxygenation and glucose uptake in tissue.Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genesTargeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell deathInteractions among genes, tumor biology and the environment in cancer health disparities: examining the evidence on a national and global scaleIn Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment.Tripartite motif 24 (Trim24/Tif1α) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor α (Rarα) inhibitionStat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugsImaging of tumor clones with differential liver colonizationDoes Radiotherapy Have Curative Potential in Metastatic Patients? The Concept of Local Therapy in Oligometastatic Breast Cancer.A signature of immune function genes associated with recurrence-free survival in breast cancer patients.Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance.Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory breast cancer cells in a signal transducer and activator of transcription 2 (STAT2)-dependent manner.CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinomaGDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.The tumor suppressor function of STAT1 in breast cancerPeriostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment.Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells.RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins.Phosphorylation meets nuclear import: a review.Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs.Portrait of inflammatory response to ionizing radiation treatment.Comparative gene-expression profiling of CD133(+) and CD133(-) D10 melanoma cells.Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome.Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy.Radiotherapy and immunotherapy: a beneficial liaison?Hypoxia modulates A431 cellular pathways association to tumor radioresistance and enhanced migration revealed by comprehensive proteomic and functional studies.Autocrine activation of the IFN signaling pathway may promote immune escape in glioblastoma.
P2860
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P2860
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@ast
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@en
type
label
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@ast
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@en
prefLabel
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@ast
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@en
P2093
P2860
P50
P1433
P1476
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy
@en
P2093
Harold G Sutton
Mara G Beveridge
Michael A Beckett
Michael Y Shao
Mihir Bhayani
Mitchell C Posner
Nikolai N Khodarev
Paul Roach
Ravi F Sood
Sean P Pitroda
P2860
P356
10.1371/JOURNAL.PONE.0005821
P407
P577
2009-06-08T00:00:00Z