about
Identifying ligand-binding hot spots in proteins using brominated fragmentsTackling the challenges posed by target flexibility in drug design.Experimental validation of a fragment library for lead discovery using SPR biosensor technology.Baicalin positively regulates osteoclast function by activating MAPK/Mitf signalling.Hit clustering can improve virtual fragment screening: CDK2 and PARP1 case studies.Advances in fragment-based drug discovery platforms.New Frontiers in DruggabilityLow potency toxins reveal dense interaction networks in metabolism.Wine Compounds as a Source for HTS Screening Collections. A Feasibility Study.Challenges and advances in computational docking: 2009 in review.When analoging is not enough: scaffold discovery in medicinal chemistry.Theoretical prediction of hydrogen-bond basicity pKBHX using quantum chemical topology descriptorsThe in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine.Comparative amino acid decomposition analysis of potent type I p38α inhibitors.2,3-Dihydroxy-quinoxaline induces ATPase activity of Herpes Simplex Virus thymidine kinase.Exhaustive sampling of the fragment space associated to a molecule leading to the generation of conserved fragments.Fragment-based drug discovery: what really works. An interview with Sandy Farmer of Boehringer Ingelheim.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Fragment-based drug discovery.
@ast
Fragment-based drug discovery.
@en
type
label
Fragment-based drug discovery.
@ast
Fragment-based drug discovery.
@en
prefLabel
Fragment-based drug discovery.
@ast
Fragment-based drug discovery.
@en
P2860
P1476
Fragment-based drug discovery.
@en
P2093
Wendy A Warr
P2860
P2888
P304
P356
10.1007/S10822-009-9292-1
P577
2009-06-24T00:00:00Z