Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area. - Wikidata - awgldk - TriplyDB

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

http://www.wikidata.org/entity/Q33489512

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Advances and challenges in malaria vaccine development Immune mechanisms in malaria: new insights in vaccine development Development and characterization of synthetic glucopyranosyl lipid adjuvant system as a vaccine adjuvant Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators T cell responses to the RTS,S/AS01(E) and RTS,S/AS02(D) malaria candidate vaccines administered according to different schedules to Ghanaian children Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data.Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data.Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.A randomized trial assessing the safety and immunogenicity of AS01 and AS02 adjuvanted RTS,S malaria vaccine candidates in children in Gabon.Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data.Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model.The burden of common infectious disease syndromes at the clinic and household level from population-based surveillance in rural and urban Kenya The RTS,S vaccine candidate for malaria.Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates.A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine.Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized Health & demographic surveillance system profile: The Kombewa health and demographic surveillance system (Kombewa HDSS).The relationship between RTS,S vaccine-induced antibodies, CD4⁺ T cell responses and protection against Plasmodium falciparum infection.A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis.Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa.From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH-F3+GLA-SE.Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy.Antigen-specific IL-2 secretion correlates with NK cell responses after immunization of Tanzanian children with the RTS,S/AS01 malaria vaccine.Results from tandem Phase 1 studies evaluating the safety, reactogenicity and immunogenicity of the vaccine candidate antigen Plasmodium falciparum FVO merozoite surface protein-1 (MSP1(42)) administered intramuscularly with adjuvant system AS01.Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines: randomized, double-blind study in malaria-naïve adults Toll-like receptor 7 mediates early innate immune responses to malaria.Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection.The Plasmodium falciparum Antigen MB2 Induces Interferon-γ and Interleukin-10 Responses in Adults in Malaria Endemic Areas of Western Kenya.Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes Recent clinical experience with vaccines using MPL- and QS-21-containing adjuvant systems.Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine.Plasmodium falciparum malaria vaccines: current status, pitfalls and future directions.Clinical development of RTS,S/AS malaria vaccine: a systematic review of clinical Phase I-III trials.An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: bridging traditional mouse malaria models and human trials.Gene-expression analysis for prediction of RTS,S-induced protection in humans.The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria.Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection.Controlled human malaria infection.

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P2860

Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

http://www.wikidata.org/entity/Q33489512

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2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area.

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Bernhards R Ogutu

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D Gray Heppner

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John N Waitumbi

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Lucas Otieno

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P2860

The global distribution of clinical episodes of Plasmodium falciparum malaria

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden.

Efficacy of the RTS,S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial.

The global distribution and population at risk of malaria: past, present, and future

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection.

Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant.

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial.

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W Ripley Ballou

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malaria transmission

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