Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action.
about
Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration4-Hydroxy-nonenal-A Bioactive Lipid Peroxidation ProductAutophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.Knock-down of cathepsin D affects the retinal pigment epithelium, impairs swim-bladder ontogenesis and causes premature death in zebrafish.Impaired autophagy in sporadic inclusion-body myositis and in endoplasmic reticulum stress-provoked cultured human muscle fibersPathological aspects of lipid peroxidation.The role of lipid peroxidation products and oxidative stress in activation of the canonical wingless-type MMTV integration site (WNT) pathway in a rat model of diabetic retinopathyOxidative stress sensitizes retinal pigmented epithelial (RPE) cells to complement-mediated injury in a natural antibody-, lectin pathway-, and phospholipid epitope-dependent manner.Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cellsSPP2 Mutations Cause Autosomal Dominant Retinitis PigmentosaLysosomes: Regulators of autophagy in the retinal pigmented epithelium.Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.UVA causes dual inactivation of cathepsin B and L underlying lysosomal dysfunction in human dermal fibroblasts.Lipid metabolites in the pathogenesis and treatment of neovascular eye disease.Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.Induced pluripotent stem cell therapies for geographic atrophy of age-related macular degeneration.Ultraviolet A Enhances Cathepsin L Expression and Activity via JNK Pathway in Human Dermal Fibroblasts.Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.Complement Component C5a Primes Retinal Pigment Epithelial Cells for Inflammasome Activation by Lipofuscin-mediated Photooxidative DamagePharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration.Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage.Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis.Effects of white light-emitting diode (LED) exposure on retinal pigment epithelium in vivo.Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal.Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4-hydroxynonenal.
P2860
Q21195877-19093F88-8E20-4F1B-910B-565F667AE76DQ26782039-B6B68B55-7029-4719-960A-60E2DC730A82Q33755432-4972CDC0-5BCE-4879-82E3-02529ADA5A46Q33958150-8A8EAE24-BCF3-433E-89E7-4FCFA98DA446Q34086965-B72D7E6D-75DC-4CF6-9D57-E589958B808AQ34137628-AB340514-0ABF-4FB9-BC43-2405CA793899Q34472694-B075FB8D-D0BD-4FB6-89E9-27BE3723FE78Q34620560-6C67EB07-0B1F-45F7-8B84-D4EB800D4B93Q34903032-B2E4F012-FB47-4E3A-BF81-14AD6BB900D1Q36149803-6262157A-00AB-48AD-8D37-E36F1A6E9AF0Q36421374-C53F0F68-AD33-4F3A-82E9-C0F91F74D659Q36626060-C6F5A57F-83D8-4896-909F-5F88CDA48510Q37010298-B5127094-F525-4BC6-AE5A-7FA5DD0E533CQ37011339-23F87B97-BD46-458A-8D7D-908C9DA52840Q37245993-A62BA8F4-3C96-4136-BFF8-0B2A6E02B6DFQ37246879-DFC5490E-AD0B-40EF-B068-BEE09C08DC39Q37487646-5079825B-1705-4080-986B-2B33E4440406Q38077549-DEB0A51D-90C1-4214-A2E0-0DA5499179F8Q38819720-530FD599-6C6B-4E0B-9B0D-030CEC633931Q39791804-CF996FB1-A798-434F-8E82-CD43D3B6B6FAQ41851269-20CE4582-3808-46C3-B996-03C70935375FQ42492505-118B0C15-6491-4BE3-A373-968E7957610AQ42511711-066D1F3A-711C-442D-8DEC-E5574869247EQ46284513-10CDAC55-18A1-4950-B53C-183635ED63B7Q48353458-B02CE059-B679-4C08-BAD8-F58088D0AA74
P2860
Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Lipid peroxidation products re ...... ifferent mechanisms of action.
@ast
Lipid peroxidation products re ...... ifferent mechanisms of action.
@en
Lipid peroxidation products re ...... ifferent mechanisms of action.
@nl
type
label
Lipid peroxidation products re ...... ifferent mechanisms of action.
@ast
Lipid peroxidation products re ...... ifferent mechanisms of action.
@en
Lipid peroxidation products re ...... ifferent mechanisms of action.
@nl
prefLabel
Lipid peroxidation products re ...... ifferent mechanisms of action.
@ast
Lipid peroxidation products re ...... ifferent mechanisms of action.
@en
Lipid peroxidation products re ...... ifferent mechanisms of action.
@nl
P1476
Lipid peroxidation products re ...... ifferent mechanisms of action.
@en
P2093
Elke Kaemmerer
Jürgen Kopitz
P304
P356
10.1016/J.EXER.2009.10.014
P577
2009-11-04T00:00:00Z