Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

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Q33521418

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Gut microbiota and colorectal cancer Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling Prevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptor Interleukin-6 contributes to inflammation and remodeling in a model of adenosine mediated lung injury Cytokines, IBD, and colitis-associated cancer Contribution of vascular cell-derived cytokines to innate and inflammatory pathways in atherogenesis.Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica.Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An Update Chronic inflammation and cytokines in the tumor microenvironment.Involvement of NF-κB/IL-6 Pathway in the Processing of Colorectal Carcinogenesis in Colitis Mice Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis gp130 at the nexus of inflammation, autoimmunity, and cancer.Recent advancement in understanding colitis-associated tumorigenesis.Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer Interleukin-6 induces S100A9 expression in colonic epithelial cells through STAT3 activation in experimental ulcerative colitis.Pericellular proteolysis in cancer IL-22 is related to development of human colon cancer by activation of STAT3.IL-6 stimulates intestinal epithelial proliferation and repair after injury.Interleukin-6 modulates graft-versus-host responses after experimental allogeneic bone marrow transplantation.Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages.PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer.IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells.Stat3: friend or foe in colitis and colitis-associated cancer?15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells.Interleukin-6 (IL-6) mediated the increased contraction of distal colon in streptozotocin-induced diabetes in rats via IL-6 receptor pathway Interleukin-6 trans-signaling increases the expression of carcinoembryonic antigen-related cell adhesion molecules 5 and 6 in colorectal cancer cells.Oral lichen planus as a preneoplastic inflammatory model.cEBP Homologous Protein Expression in Macrophages Regulates the Magnitude and Duration of IL-6 Expression and Dextran Sodium Sulfate Colitis Expression of NF-κB and IL-6 in oral precancerous and cancerous lesions: An immunohistochemical study Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer.The soluble interleukin-6 receptor is a mediator of hematopoietic and skeletal actions of parathyroid hormone.Trp53 deficiency protects against acute intestinal inflammation.ADAM Proteases and Gastrointestinal Function.Increased levels of IL-6, sIL-6R, and sgp130 in the aqueous humor and serum of patients with diabetic retinopathy.Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma.IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis.A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model.Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer.

P2860

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P2860

Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.

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http://www.wikidata.org/entity/Q33521418

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2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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