A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
about
Computerized advice on drug dosage to improve prescribing practiceSystemic therapies for pancreatic cancer--the role of pharmacogeneticsIrinotecan pharmacogenomicsPhase-I dose finding and pharmacokinetic study of the novel hydrophilic camptothecin ST-1968 (namitecan) in patients with solid tumors.Effects of mannose-binding lectin polymorphisms on irinotecan-induced febrile neutropenia.Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRIClinical validity of new genetic biomarkers of irinotecan neutropenia: an independent replication study.Translational studies of phenotypic probes for the mononuclear phagocyte system and liposomal pharmacology.Ethnic differences in the metabolism, toxicology and efficacy of three anticancer drugs.CYP3A activity: towards dose adaptation to the individual.Sequential designs for individualized dosing in phase I cancer clinical trials.Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients.Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs.Use of microdose phenotyping to individualise dosing of patients.Evaluation of a pharmacology-driven dosing algorithm of 3-weekly paclitaxel using therapeutic drug monitoring: a pharmacokinetic-pharmacodynamic simulation study.CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin.Clarithromycin co-administration does not increase irinotecan (CPT-11) toxicity in colorectal cancer patients.Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics.Relevance of CYP3A4*20, UGT1A1*37 and UGT1A1*28 variants in irinotecan-induced severe toxicity.Integrating rare genetic variants into pharmacogenetic drug response predictions.
P2860
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P2860
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@ast
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@en
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@nl
type
label
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@ast
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@en
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@nl
prefLabel
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@ast
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@en
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@nl
P2093
P1476
A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
@en
P2093
André S Th Planting
Erik A C Wiemer
Floris A de Jong
Geert-Jan M Creemers
Jaap Verweij
Jessica M van der Bol
Lena E Friberg
Ron H J Mathijssen
Walter J Loos
P304
P356
10.1158/1078-0432.CCR-09-1526
P407
P577
2010-01-12T00:00:00Z