Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.
about
ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseCrmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation.CRMP5 regulates generation and survival of newborn neurons in olfactory and hippocampal neurogenic areas of the adult mouse brainSemaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosisShared resistance to aging and ALS in neuromuscular junctions of specific muscles.Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status.Progress in therapy development for amyotrophic lateral sclerosisPhosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.Death Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis.CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon ElongationExpression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic MuscleMotor neuron-immune interactions: the vicious circle of ALS.Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders.Dysregulation of axonal transport and motorneuron diseases.Class 3 semaphorins as a therapeutic target.Advances in cellular models to explore the pathophysiology of amyotrophic lateral sclerosis.The emerging role of class-3 semaphorins and their neuropilin receptors in oncology.CRMPs Function in Neurons and Glial Cells: Potential Therapeutic Targets for Neurodegenerative Diseases and CNS Injury.The Axon Guidance Protein Semaphorin 3A Is Increased in the Motor Cortex of Patients With Amyotrophic Lateral Sclerosis.Deletion of collapsin response mediator protein 4 results in abnormal layer thickness and elongation of mitral cell apical dendrites in the neonatal olfactory bulb.Collapsin response mediator protein 4 affects the number of tyrosine hydroxylase-immunoreactive neurons in the sexually dimorphic nucleus in female mice.Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations.A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS.Proteomic profiling of the spinal cord in ALS: decreased ATP5D levels suggest synaptic dysfunction in ALS pathogenesis.Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.Loss of collapsin response mediator protein 4 suppresses dopaminergic neuron death in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
P2860
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P2860
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Collapsin response mediator pr ...... l degeneration and cell death.
@ast
Collapsin response mediator pr ...... l degeneration and cell death.
@en
Collapsin response mediator protein 4a
@nl
type
label
Collapsin response mediator pr ...... l degeneration and cell death.
@ast
Collapsin response mediator pr ...... l degeneration and cell death.
@en
Collapsin response mediator protein 4a
@nl
prefLabel
Collapsin response mediator pr ...... l degeneration and cell death.
@ast
Collapsin response mediator pr ...... l degeneration and cell death.
@en
Collapsin response mediator protein 4a
@nl
P2093
P50
P1476
Collapsin response mediator pr ...... al degeneration and cell death
@en
P2093
Brigitte Pettmann
Béatrice De Bovis
Eric Thouvenot
Jérôme Honnorat
Keith Dudley
Laure Duplan
Nathalie Bernard
Patrick Aebischer
Philippe Marin
Wilfrid Casseron
P304
P356
10.1523/JNEUROSCI.5411-09.2010
P407
P577
2010-01-01T00:00:00Z