An improved yeast transformation method for the generation of very large human antibody libraries.
about
In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid LibrariesCells and cell lysates: a direct approach for engineering antibodies against membrane proteins using yeast surface displayRational HIV Immunogen Design to Target Specific Germline B Cell ReceptorsOptimization of affinity, specificity and function of designed influenza inhibitors using deep sequencingComputational design of ligand-binding proteins with high affinity and selectivityExploration of Alternate Catalytic Mechanisms and Optimization Strategies for Retroaldolase DesignEngineering an Anti-Transferrin Receptor ScFv for pH-Sensitive Binding Leads to Increased Intracellular AccumulationDetermination of ubiquitin fitness landscapes under different chemical stresses in a classroom settingDetermination of binding affinity upon mutation for type I dockerin-cohesin complexes from Clostridium thermocellum and Clostridium cellulolyticum using deep sequencingFine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin.Mining human antibody repertoires.Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity.Reiterative Recombination for the in vivo assembly of libraries of multigene pathways.Peptide aptamers: development and applications.Functional heterologous protein expression by genetically engineered probiotic yeast Saccharomyces boulardii.Frontier of therapeutic antibody discovery: The challenges and how to face them.Rapid optimization and prototyping for therapeutic antibody-like molecules.Potential use of potassium efflux-deficient yeast for studying trafficking signals and potassium channel functions.Combinatorial engineering of mevalonate pathway for improved amorpha-4,11-diene production in budding yeast.Therapeutic antibody engineering by high efficiency cell screening.Screening a random mutagenesis library of a fungal β-fructofuranosidase using FT-MIR ATR spectroscopy and multivariate analysis.Computational design of a pH-sensitive IgG binding protein.REAL-Select: full-length antibody display and library screening by surface capture on yeast cells.A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast displayAn engineered autotransporter-based surface expression vector enables efficient display of Affibody molecules on OmpT-negative E. coli as well as protease-mediated secretion in OmpT-positive strains.High-resolution sequence-function mapping of full-length proteins.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).The Shark Strikes Twice: Hypervariable Loop 2 of Shark IgNAR Antibody Variable Domains and Its Potential to Function as an Autonomous Paratope.Combining Phage and Yeast Cell Surface Antibody Display to Identify Novel Cell Type-Selective Internalizing Human Monoclonal AntibodiesT Cell Receptor Engineering and Analysis Using the Yeast Display Platform.N-Terminal Coiled-Coil Structure of ATPase Subunits of 26S Proteasome Is Crucial for Proteasome FunctionHigh-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin DomainsEngineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library ScreeningEfficient construct of a large and functional scFv yeast display library derived from the ascites B cells of ovarian cancer patients by three-fragment transformation-associated recombination.Isolation of a pH-Sensitive IgNAR Variable Domain from a Yeast-Displayed, Histidine-Doped Master Library.Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals.Selection of Recombinant Human Antibodies.A simplified procedure for antibody engineering by yeast surface display: Coupling display levels and target binding by ribosomal skipping.Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-Ig(TM)) molecule that specifically and potently neutralizes both IL-1α and IL-1β.Low-stringency selection of TEM1 for BLIP shows interface plasticity and selection for faster binders.
P2860
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P2860
An improved yeast transformation method for the generation of very large human antibody libraries.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An improved yeast transformati ...... arge human antibody libraries.
@ast
An improved yeast transformati ...... arge human antibody libraries.
@en
An improved yeast transformati ...... arge human antibody libraries.
@nl
type
label
An improved yeast transformati ...... arge human antibody libraries.
@ast
An improved yeast transformati ...... arge human antibody libraries.
@en
An improved yeast transformati ...... arge human antibody libraries.
@nl
prefLabel
An improved yeast transformati ...... arge human antibody libraries.
@ast
An improved yeast transformati ...... arge human antibody libraries.
@en
An improved yeast transformati ...... arge human antibody libraries.
@nl
P2093
P2860
P356
P1476
An improved yeast transformati ...... arge human antibody libraries.
@en
P2093
Chung-Ming Hsieh
Jennifer M Perez
Jonathan Belk
Lorenzo Benatuil
P2860
P304
P356
10.1093/PROTEIN/GZQ002
P577
2010-02-03T00:00:00Z