Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase.

Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase.

Item
http://www.wikidata.org/entity/Q33535643
Unstable reaction intermediates and hysteresis during the catalytic cycle of 5-aminolevulinate synthase: implications from using pseudo and alternate substrates and a promiscuous enzyme variant.Molecular enzymology of 5-aminolevulinate synthase, the gatekeeper of heme biosynthesis.Functional asymmetry for the active sites of linked 5-aminolevulinate synthase and 8-amino-7-oxononanoate synthase.Expression of murine 5-aminolevulinate synthase variants causes protoporphyrin IX accumulation and light-induced mammalian cell deathCatalytically active alkaline molten globular enzyme: Effect of pH and temperature on the structural integrity of 5-aminolevulinate synthaseAsn-150 of Murine Erythroid 5-Aminolevulinate Synthase Modulates the Catalytic Balance between the Rates of the Reversible ReactionHuman Erythroid 5-Aminolevulinate Synthase Mutations Associated with X-Linked Protoporphyria Disrupt the Conformational Equilibrium and Enhance Product Release.X-linked sideroblastic anemia due to carboxyl-terminal ALAS2 mutations that cause loss of binding to the β-subunit of succinyl-CoA synthetase (SUCLA2).Molecular expression and characterization of erythroid-specific 5-aminolevulinate synthase gain-of-function mutations causing X-linked protoporphyriaInvestigating the bifunctionality of cyclizing and "classical" 5-aminolevulinate synthases.5-Aminolevulinic acid production from inexpensive glucose by engineering the C4 pathway in Escherichia coli.Molecular dynamics analysis of the structural and dynamic properties of the functionally enhanced hepta-variant of mouse 5-aminolevulinate synthase.Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme.
P2860

Targeting the active site gate to yield hyperactive variants of 5-aminolevulinate synthase.

Item
http://www.wikidata.org/entity/Q33535643
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@ast
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@en
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@nl
type
label
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@ast
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@en
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@nl
prefLabel
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@ast
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@en
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Targeting the active site gate ...... of 5-aminolevulinate synthase.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932