The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.
about
The peroxisome proliferator-activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy.Pulmonary hypertension and metabolic syndrome: Possible connection, PPARγ and Caveolin-1New perspectives for the treatment of pulmonary hypertensionRole of prostacyclin in pulmonary hypertension.Novel therapeutic approaches to preserve the right ventricle.Relaxation of human pulmonary arteries by PPARγ agonists.Peroxisome proliferation-activated receptor δ agonist GW0742 interacts weakly with multiple nuclear receptors, including the vitamin D receptor.Fatty acid metabolism in pulmonary arterial hypertension: role in right ventricular dysfunction and hypertrophy.Novel investigational therapies for treating pulmonary arterial hypertension.Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation.The PPARδ agonist GW0742 inhibits neuroinflammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation.Cyclooxygenase-2 Selectively Controls Renal Blood Flow Through a Novel PPARβ/δ-Dependent Vasodilator Pathway.Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold.Pulmonary hypertension: Molecular aspects of current therapeutic intervention and future direction.Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation.Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension.
P2860
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P2860
The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@ast
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@en
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@nl
type
label
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@ast
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@en
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@nl
prefLabel
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@ast
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@en
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@nl
P2093
P2860
P1433
P1476
The PPARbeta/delta agonist GW0 ...... nduced pulmonary hypertension.
@en
P2093
Christopher Garland
Jane A Mitchell
Louise S Harrington
Stephen J Wort
P2860
P356
10.1371/JOURNAL.PONE.0009526
P407
P577
2010-03-04T00:00:00Z