about
The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth controlTwo-round coamplification at lower denaturation temperature-PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinoma[6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cellsJasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cellsRole of the p53/p21 system in the response of human colon carcinoma cells to DoxorubicinImpaired DNA replication within progenitor cell pools promotes leukemogenesis.Emerging role of cancer stem cells in the biology and treatment of ovarian cancer: basic knowledge and therapeutic possibilities for an innovative approachInhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genesPreclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomographyHeterogeneous biomedical database integration using a hybrid strategy: a p53 cancer research database.Irradiation selects for p53-deficient hematopoietic progenitors.COLD-PCR-enhanced high-resolution melting enables rapid and selective identification of low-level unknown mutationsThe multiple facets of drug resistance: one history, different approaches.Apoptosis in cancer.Defect in the p53-Mdm2 autoregulatory loop resulting from inactivation of TAF(II)250 in cell cycle mutant tsBN462 cells.Cancer stem cells as targets for cancer therapy: selected cancers as examples.How apoptosis is regulated, and what goes wrong in cancerRequirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.Paradox of Bcl-2 (and p53): why may apoptosis-regulating proteins be irrelevant to cell death?Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape.A protein turnover signaling motif controls the stimulus-sensitivity of stress response pathwaysSignificance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.Methods for screening tumors for p53 status and therapeutic exploitation.Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic responseINK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.Signaling from p53 to NF-kappa B determines the chemotherapy responsiveness of neuroblastoma.Cyclophosphamide dose intensification may circumvent anthracycline resistance of p53 mutant breast cancers.Low expression of phosphatase and tensin homolog in clear‑cell renal cell carcinoma contributes to chemoresistance through activating the Akt/HDM2 signaling pathway.Biomarkers in the molecular pathogenesis of esophageal (Barrett) adenocarcinoma.Exploiting the p53 pathway for the diagnosis and therapy of human cancer.Serum p53 antibodies: predictors of survival in small-cell lung cancer?Neem oil limonoids induces p53-independent apoptosis and autophagy.Replicational stress selects for p53 mutationDNA damage response and development of targeted cancer treatments.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesp53: a molecular marker for the detection of cancer.Plasmid-based E6-specific siRNA and co-expression of wild-type p53 suppresses the growth of cervical cancer in vitro and in vivo.Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer.VHL missense mutations in the p53 binding domain show different effects on p53 signaling and HIFα degradation in clear cell renal cell carcinoma.Overcoming challenges of ovarian cancer stem cells: novel therapeutic approaches.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Clinical implications of p53 mutations.
@ast
Clinical implications of p53 mutations.
@en
Clinical implications of p53 mutations.
@nl
type
label
Clinical implications of p53 mutations.
@ast
Clinical implications of p53 mutations.
@en
Clinical implications of p53 mutations.
@nl
prefLabel
Clinical implications of p53 mutations.
@ast
Clinical implications of p53 mutations.
@en
Clinical implications of p53 mutations.
@nl
P356
P1476
Clinical implications of p53 mutations.
@en
P2093
Wallace-Brodeur RR
P2888
P356
10.1007/S000180050270
P577
1999-01-01T00:00:00Z