Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences

Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences

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http://www.wikidata.org/entity/Q33545560
CD8(+)T-cell-mediated control of HIV-1 and SIV infection.Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection.Indel and Carryforward Correction (ICC): a new analysis approach for processing 454 pyrosequencing dataTransmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.The efficiency of the human CD8+ T cell response: how should we quantify it, what determines it, and does it matter?Improved detection of rare HIV-1 variants using 454 pyrosequencing.Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection.Systems biology approaches to new vaccine development.Comparison of Major and Minor Viral SNPs Identified through Single Template Sequencing and Pyrosequencing in Acute HIV-1 Infection.Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL EscapesA quantitative quasispecies theory-based model of virus escape mutation under immune selectionPreviously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions.Restriction of V3 region sequence divergence in the HIV-1 envelope gene during antiretroviral treatment in a cohort of recent seroconverters.Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum.The HIV-1 transmission bottleneck.Kinetics of HIV-Specific CTL Responses Plays a Minimal Role in Determining HIV Escape Dynamics.
P2860

Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences

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http://www.wikidata.org/entity/Q33545560
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Mathematical modeling of ultra ...... lear founder epitope sequences
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Mathematical modeling of ultra ...... lear founder epitope sequences
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Mathematical modeling of ultra ...... ear founder epitope sequences.
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type
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Mathematical modeling of ultra ...... lear founder epitope sequences
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Mathematical modeling of ultra ...... lear founder epitope sequences
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Mathematical modeling of ultra ...... ear founder epitope sequences.
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prefLabel
Mathematical modeling of ultra ...... lear founder epitope sequences
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Mathematical modeling of ultra ...... lear founder epitope sequences
@en
Mathematical modeling of ultra ...... ear founder epitope sequences.
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Mathematical modeling of ultra ...... lear founder epitope sequences
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P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932