In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.
about
The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activationIsolation and chemical characterization of Alzheimer's disease paired helical filament cytoskeletons: differentiation from amyloid plaque core proteinEnzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brainBeta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.Differential effect of zinc finger deletions on the binding of CTCF to the promoter of the amyloid precursor protein gene.Alternative polyadenylation of the amyloid protein precursor mRNA regulates translationhnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodiesThe beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells.Regulation of mRNA stability in the nervous system and beyond.USF binds to the APB alpha sequence in the promoter of the amyloid beta-protein precursor gene.Transthyretin sequesters amyloid beta protein and prevents amyloid formation.Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.Widespread expression of amyloid beta-protein precursor gene in rat brain.Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease.The promoter of Alzheimer's disease amyloid A4 precursor geneThe amyloid precursor protein copper binding domain histidine residues 149 and 151 mediate APP stability and metabolism.Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function.Processing of the Alzheimer's disease beta A4 amyloid protein precursor (APP).Amyloid precursor protein in aged nonhuman primates.Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.Altered levels of amyloid protein precursor transcripts in the basal forebrain of behaviorally impaired aged rats.Molecular genetics of Alzheimer's disease and the amyloid beta peptide precursor gene.The role of cytosolic phospholipase A2 α in amyloid precursor protein induction by amyloid beta1-42 : implication for neurodegeneration.Calcium-activated neutral proteinases as regulators of cellular function. Implications for Alzheimer's disease pathogenesis.Interleukin-1beta and glutamate activate the NF-kappaB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures.Relationships among the cerebral amyloid peptides and their precursors.Image analysis microspectroscopy shows that neurons participate in the genesis of a subset of early primitive (diffuse) senile plaques.Identification and characterization of a kappa B/Rel binding site in the regulatory region of the amyloid precursor protein gene.Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.Analysis of mouse intron 7 DNA sequence of the APP gene: comparison with the human homologue.Alzheimer's disease. Beta-amyloid precursor protein expression in the nucleus basalis of Meynert.APP RNA splicing is not affected by differentiation of neurons and glia in culture.Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.Amyloid deposition is associated with c-Jun expression in Alzheimer's disease and amyloid angiopathy.Molecular mechanisms of glutamate-induced neurodegenerationUltrastructural and biochemical basis of Alzheimer's diseaseSpecific patterns of amyloid β-protein precursor isoform secretion and proteolysis in cultured human cells
P2860
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P2860
In situ hybridization of nucleus basalis neurons shows increased beta-amyloid mRNA in Alzheimer disease.
description
1988 nî lūn-bûn
@nan
1988 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@ast
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@en
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@nl
type
label
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@ast
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@en
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@nl
prefLabel
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@ast
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@en
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@nl
P2093
P2860
P356
P1476
In situ hybridization of nucle ...... oid mRNA in Alzheimer disease.
@en
P2093
L H Younkin
S G Younkin
P2860
P304
P356
10.1073/PNAS.85.4.1227
P407
P577
1988-02-01T00:00:00Z